Hydroxychloroquine is metabolized by CYP2D6, CYP3A4, and CYP2C8, and inhibits CYP2D6, while its metabolites also inhibit CYP3A in vitro

Marie-Noëlle Paludetto, Mika Kurkela, Helinä Kahma, Janne T. Backman, Mikko Niemi, Anne Filppula

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Drug Metabolism and Disposition
DOIs	https://doi.org/10.1124/dmd.122.001018
Publication status	Published - 29 Nov 2022

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title = "Hydroxychloroquine is metabolized by CYP2D6, CYP3A4, and CYP2C8, and inhibits CYP2D6, while its metabolites also inhibit CYP3A in vitro",

author = "Marie-No{\"e}lle Paludetto and Mika Kurkela and Helin{\"a} Kahma and Backman, {Janne T.} and Mikko Niemi and Anne Filppula",

year = "2022",

month = nov,

day = "29",

doi = "10.1124/dmd.122.001018",

language = "English",

journal = "Drug Metabolism and Disposition",

issn = "0090-9556",

publisher = "Elsevier BV",

}

TY - JOUR

T1 - Hydroxychloroquine is metabolized by CYP2D6, CYP3A4, and CYP2C8, and inhibits CYP2D6, while its metabolites also inhibit CYP3A in vitro

AU - Paludetto, Marie-Noëlle

AU - Kurkela, Mika

AU - Kahma, Helinä

AU - Backman, Janne T.

AU - Niemi, Mikko

AU - Filppula, Anne

PY - 2022/11/29

Y1 - 2022/11/29

UR - http://dx.doi.org/10.1124/dmd.122.001018

U2 - 10.1124/dmd.122.001018

DO - 10.1124/dmd.122.001018

M3 - Article

SN - 0090-9556

JO - Drug Metabolism and Disposition

JF - Drug Metabolism and Disposition

ER -