Imaging language pathways predicts postoperative naming deficits

H. W R Powell; G. J M Parker; D. C. Alexander; M. R. Symms; P. A. Boulby; G. J. Barker; P. J. Thompson; M. J. Koepp; John S. Duncan

doi:10.1136/jnnp.2007.126078

Imaging language pathways predicts postoperative naming deficits

H. W R Powell, G. J M Parker, D. C. Alexander, M. R. Symms, P. A. Boulby, G. J. Barker, P. J. Thompson, M. J. Koepp, John S. Duncan

Research output: Contribution to journal › Article › peer-review

Abstract

Naming difficulties are a well recognised, but difficult to predict, complication of anterior temporal lobe resection (ATLR) for refractory epilepsy. We used MR tractography preoperatively to demonstrate the structural connectivity of language areas in patients undergoing dominant hemisphere ATLR. Greater lateralisation of tracts to the dominant hemisphere was associated with greater decline in naming function. We suggest that this method has the potential to predict language deficits in patients undergoing ATLR.

Original language	English
Pages (from-to)	327-330
Number of pages	3
Journal	Journal of Neurology, Neurosurgery and Psychiatry
Volume	79
Issue number	3
DOIs	https://doi.org/10.1136/jnnp.2007.126078
Publication status	Published - Mar 2008

Keywords

Adult
Age of Onset
adverse effects: Anterior Temporal Lobectomy
Brain Mapping
Electroencephalography
diagnosis: Epilepsy, Temporal Lobe
Female
pathology: Frontal Lobe
Functional Laterality
Humans
diagnosis: Language Disorders
Magnetic Resonance Imaging
Male

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10.1136/jnnp.2007.126078

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title = "Imaging language pathways predicts postoperative naming deficits",

abstract = "Naming difficulties are a well recognised, but difficult to predict, complication of anterior temporal lobe resection (ATLR) for refractory epilepsy. We used MR tractography preoperatively to demonstrate the structural connectivity of language areas in patients undergoing dominant hemisphere ATLR. Greater lateralisation of tracts to the dominant hemisphere was associated with greater decline in naming function. We suggest that this method has the potential to predict language deficits in patients undergoing ATLR.",

keywords = "Adult, Age of Onset, adverse effects: Anterior Temporal Lobectomy, Brain Mapping, Electroencephalography, diagnosis: Epilepsy, Temporal Lobe, Female, pathology: Frontal Lobe, Functional Laterality, Humans, diagnosis: Language Disorders, Magnetic Resonance Imaging, Male",

author = "Powell, {H. W R} and Parker, {G. J M} and Alexander, {D. C.} and Symms, {M. R.} and Boulby, {P. A.} and Barker, {G. J.} and Thompson, {P. J.} and Koepp, {M. J.} and Duncan, {John S.}",

year = "2008",

month = mar,

doi = "10.1136/jnnp.2007.126078",

language = "English",

volume = "79",

pages = "327--330",

journal = "Journal of Neurology, Neurosurgery and Psychiatry",

issn = "0022-3050",

publisher = "BMJ ",

number = "3",

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TY - JOUR

T1 - Imaging language pathways predicts postoperative naming deficits

AU - Powell, H. W R

AU - Parker, G. J M

AU - Alexander, D. C.

AU - Symms, M. R.

AU - Boulby, P. A.

AU - Barker, G. J.

AU - Thompson, P. J.

AU - Koepp, M. J.

AU - Duncan, John S.

PY - 2008/3

Y1 - 2008/3

N2 - Naming difficulties are a well recognised, but difficult to predict, complication of anterior temporal lobe resection (ATLR) for refractory epilepsy. We used MR tractography preoperatively to demonstrate the structural connectivity of language areas in patients undergoing dominant hemisphere ATLR. Greater lateralisation of tracts to the dominant hemisphere was associated with greater decline in naming function. We suggest that this method has the potential to predict language deficits in patients undergoing ATLR.

AB - Naming difficulties are a well recognised, but difficult to predict, complication of anterior temporal lobe resection (ATLR) for refractory epilepsy. We used MR tractography preoperatively to demonstrate the structural connectivity of language areas in patients undergoing dominant hemisphere ATLR. Greater lateralisation of tracts to the dominant hemisphere was associated with greater decline in naming function. We suggest that this method has the potential to predict language deficits in patients undergoing ATLR.

KW - Adult

KW - Age of Onset

KW - adverse effects: Anterior Temporal Lobectomy

KW - Brain Mapping

KW - Electroencephalography

KW - diagnosis: Epilepsy, Temporal Lobe

KW - Female

KW - pathology: Frontal Lobe

KW - Functional Laterality

KW - Humans

KW - diagnosis: Language Disorders

KW - Magnetic Resonance Imaging

KW - Male

U2 - 10.1136/jnnp.2007.126078

DO - 10.1136/jnnp.2007.126078

M3 - Article

SN - 0022-3050

VL - 79

SP - 327

EP - 330

JO - Journal of Neurology, Neurosurgery and Psychiatry

JF - Journal of Neurology, Neurosurgery and Psychiatry

IS - 3

ER -

Imaging language pathways predicts postoperative naming deficits

Abstract

Keywords

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