Imaging tumor vascular heterogeneity and angiogenesis using dynamic contrast-enhanced magnetic resonance imaging

Research output: Contribution to journalArticlepeer-review

Abstract

This article reviews the application of dynamic contrast-enhanced magnetic resonance imaging in both clinical studies and early-phase trials of angiogenesis inhibitors. Emphasis is placed on how variation in image acquisition and analysis affects the meaning and use of derived variables. We then review the potential for future developments, with particular reference to the application of dynamic contrast-enhanced magnetic resonance imaging to evaluate the heterogeneity of tumor tissues.

Original languageEnglish
Pages (from-to)3449-59
Number of pages11
JournalClinical Cancer Research
Volume13
Issue number12
DOIs
Publication statusPublished - 15 Jun 2007

Keywords

  • Angiogenesis Inhibitors
  • Animals
  • Clinical Trials as Topic
  • Humans
  • Image Enhancement
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Neoplasms
  • Neovascularization, Pathologic
  • Radiography
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review

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