IMGT, the international ImMunoGeneTics database

Marie Paule Lefranc, Véronique Giudicelli, Chantal Ginestoux, Julia Bodmer, Werner Müller, Ronald Bontrop, Marc Lemaitre, Ansar Malik, Valérie Barbié, Denys Chaume

    Research output: Contribution to journalArticlepeer-review

    Abstract

    IMGT, the international ImMunoGeneTics database (http://imgt.cnusc.fr:8104), is a high-quality integrated database specialising in Immunoglobulins (Ig), T cell Receptors (TcR) and Major Histocompatibility Complex (MHC) molecules of all vertebrate species, created in 1989 by Marie-Paule Lefranc, Universite Montpellier II, CNRS, Montpellier, France (lefranc@@@ligm.igh.cnrs.fr). IMGT comprises three databases: LIGM-DB, a comprehensive database of Ig and TcR, MHC/HLA-DB, and PRIMER-DB (the last two in development); a tool, IMGT/DNAPLOT, developed for sequence analysis and alignments; and expertised data based on the IMGT scientific chart, the IMGT repertoire. By its high quality and its easy data distribution, IMGT has important implications in medical research (repertoire in autoimmune diseases, AIDS, leukemias, lymphomas), therapeutic approaches (antibody engineering), genome diversity and genome evolution studies. IMGT is freely available at http://imgt.cnusc.fr:8104.
    Original languageEnglish
    Pages (from-to)209-212
    Number of pages3
    JournalNucleic acids research.
    Volume27
    Issue number1
    DOIs
    Publication statusPublished - 1 Jan 1999

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