Immunoadsorption Techniques and Its Current Role in the Intensive Care Unit

Patrick Hamilton, Rhodri Harris, Sandip Mitra

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Immunoadsorption is an extracorporeal technique used for the removal of antibodies and molecules from the blood. A large number of different adsorbents are now available allowing for the non-selective removal of all subclasses of immunoglobulins such as IgG or more selective removal of disease specific molecules such as lipoprotein(a) and CRP. This selectivity, coupled with its highly efficient removal of the molecule, along with a favourable side-effect profile, has made immunoadsorption an attractive option in a range of autoimmune diseases. Here we discuss the mechanism and technique of immunoadsorption and review the current evidence and indications for its use, particularly in relation to sepsis.
Original languageEnglish
Title of host publicationAspects in Continuous Renal Replacement Therapy
EditorsAyman Karkar
Place of PublicationLondon
PublisherIntechOpen
ISBN (Electronic)978-1-78985-586-9
ISBN (Print)978-1-78985-585-2
DOIs
Publication statusPublished - 17 Apr 2019

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