Abstract
An enzyme-linked immunosorbent assay (ELISA) developed to determine aflatoxin in food was adapted to analyse rapidly human serum for aflatoxin. Sera from subjects in the U.K., Nigeria and Nepal were studied. No aflatoxin was found in U.K. sera, whilst 76% and 100% respectively of Nigerian and Nepalese samples were found positive for aflatoxin. Study was also made of maternal and cord sera from Thai subjects. Only 6% of maternal blood had detectable aflatoxin whilst 49% of cord sera were found positive for aflatoxin. This is evidence of trans-placental transfer of aflatoxin in humans and possibly of concentration of aflatoxin by the feto-placental unit.
| Original language | English |
|---|---|
| Pages (from-to) | 69-79 |
| Number of pages | 11 |
| Journal | Toxin Reviews |
| Volume | 8 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - 1 Jan 1989 |