Immunochemical evidence for a gastrin-like peptide in insect neuroendocrine system

K. J. Kramer; R. D. Speirs; C. N. Childs

Immunochemical evidence for a gastrin-like peptide in insect neuroendocrine system

K. J. Kramer, R. D. Speirs, C. N. Childs

Research output: Contribution to journal › Article › peer-review

Abstract

Evidence demonstrating that the neuroendocrine system (brain, corpus cardiacum, and corpus allatum) of the tobacco hornworm, Manduca sexta (L.), contains a peptide that is gastrin-like in its antigenicity, size, and susceptibility to degradative enzymes is presented. No immunoreactive gastrin was found in gut extracts from four species of insects. These results suggest the existence of a peptide in insect nervous tissue having structural similarities to vertebrate gastrin.

Original language	English
Pages (from-to)	423-426
Number of pages	3
Journal	General and comparative endocrinology
Volume	32
Issue number	4
Publication status	Published - 1977

Keywords

analysis: Beetles
analysis: Diptera
analysis: Gastrins
analysis: Houseflies
Humans
analysis: Insects
Larva
analysis: Moths
analysis: Neurosecretory Systems
analysis: Peptides
Radioimmunoassay
Species Specificity

Cite this

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title = "Immunochemical evidence for a gastrin-like peptide in insect neuroendocrine system",

abstract = "Evidence demonstrating that the neuroendocrine system (brain, corpus cardiacum, and corpus allatum) of the tobacco hornworm, Manduca sexta (L.), contains a peptide that is gastrin-like in its antigenicity, size, and susceptibility to degradative enzymes is presented. No immunoreactive gastrin was found in gut extracts from four species of insects. These results suggest the existence of a peptide in insect nervous tissue having structural similarities to vertebrate gastrin.",

keywords = "analysis: Beetles, analysis: Diptera, analysis: Gastrins, analysis: Houseflies, Humans, analysis: Insects, Larva, analysis: Moths, analysis: Neurosecretory Systems, analysis: Peptides, Radioimmunoassay, Species Specificity",

author = "Kramer, {K. J.} and Speirs, {R. D.} and Childs, {C. N.}",

year = "1977",

language = "English",

volume = "32",

pages = "423--426",

journal = "General and comparative endocrinology",

issn = "0016-6480",

publisher = "Elsevier BV",

number = "4",

}

TY - JOUR

T1 - Immunochemical evidence for a gastrin-like peptide in insect neuroendocrine system

AU - Kramer, K. J.

AU - Speirs, R. D.

AU - Childs, C. N.

PY - 1977

Y1 - 1977

N2 - Evidence demonstrating that the neuroendocrine system (brain, corpus cardiacum, and corpus allatum) of the tobacco hornworm, Manduca sexta (L.), contains a peptide that is gastrin-like in its antigenicity, size, and susceptibility to degradative enzymes is presented. No immunoreactive gastrin was found in gut extracts from four species of insects. These results suggest the existence of a peptide in insect nervous tissue having structural similarities to vertebrate gastrin.

AB - Evidence demonstrating that the neuroendocrine system (brain, corpus cardiacum, and corpus allatum) of the tobacco hornworm, Manduca sexta (L.), contains a peptide that is gastrin-like in its antigenicity, size, and susceptibility to degradative enzymes is presented. No immunoreactive gastrin was found in gut extracts from four species of insects. These results suggest the existence of a peptide in insect nervous tissue having structural similarities to vertebrate gastrin.

KW - analysis: Beetles

KW - analysis: Diptera

KW - analysis: Gastrins

KW - analysis: Houseflies

KW - Humans

KW - analysis: Insects

KW - Larva

KW - analysis: Moths

KW - analysis: Neurosecretory Systems

KW - analysis: Peptides

KW - Radioimmunoassay

KW - Species Specificity

M3 - Article

SN - 0016-6480

VL - 32

SP - 423

EP - 426

JO - General and comparative endocrinology

JF - General and comparative endocrinology

IS - 4

ER -

Immunochemical evidence for a gastrin-like peptide in insect neuroendocrine system

Abstract

Keywords

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