Impact of hepatic cirrhosis on outcome in adult cardiac surgery.

Ioannis Dimarakis, Stuart Grant, Rebecca Corless, Theodore Velissaris, Martin Prince, Ben Bridgewater, George Asimakopoulos

    Research output: Contribution to journalArticlepeer-review


    Increasing prevalence of hepatic disease is likely to translate in a growing number of patients with significant hepatic disease requiring cardiac surgery. Available cardiac risk stratification models do not address the risk associated with hepatic disease. However, weighted mean mortality rates based on previous studies of cardiac surgery in patients with hepatic disease demonstrate operative mortality rates that range from 9.88% (standard deviation [SD] 9.69) for patients in Child-Turcotte-Pugh (CTP) class A cirrhosis to 69.23% (SD 28.55) for patients with CTP class C cirrhosis. This review comprehensively appraises the pathophysiology of hepatic disease, reported clinical outcomes and considerations for risk stratification.
    Original languageEnglish
    JournalThe Thoracic and cardiovascular surgeon
    Issue number1
    Publication statusPublished - Feb 2015


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