Impact of stents on urological complications and health care expenditure in renal transplant recipients: results of a prospective, randomized clinical trial

A Tavakoli, R S Surange, R C Pearson, N R Parrott, T Augustine, H N Riad

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE: We performed a randomized, prospective trial to compare the incidence of early urological complications and health care expenditures in renal transplant recipients with or without ureteral stenting.

MATERIALS AND METHODS: Patients receiving a renal transplant at a single center were randomized preoperatively to undergo Double-J stent or no-stent ureterovesical anastomosis from November 1998 to October 2001. Early urological mechanical complications were recorded, including urinary leakage or obstruction, or urinary tract infections within 3 months of transplantation. Direct health care costs associated with stenting, urological complications and urinary tract infection management were also collected.

RESULTS: A total of 201 patients were randomized to a stent (112) and a no-stent (89) group. In the no-stent group 11 patients received a stent due to intraoperative findings and were excluded from study. At 3 months there were significantly more cases of urinary leakage (8.9% vs 0.9%, p <0.008) and ureteral obstruction (7.7 % vs 0%, p <0.004) in the no-stent than in the stent group. Mean time of stent removal was 74.3 days. A significant increase in urinary tract infections was observed when stent was left greater than 30 days after transplantation compared to the rate in the no-stent group (p <0.02). An additional cost of 151 UK pounds per patient was incurred in the no-stent group vs the stent group.

CONCLUSIONS: Using a ureteral stent at renal transplantation significantly decreases the early urinary complications of urine leakage and obstruction. However, there is a significant increase in urinary tract infections, primarily beyond 30 days after transplantation. Stent removal within 4 weeks of insertion appears advisable.

Original languageEnglish
Pages (from-to)2260-2264
JournalThe Journal of urology
Volume177
Issue number6
DOIs
Publication statusPublished - Jun 2007

Keywords

  • Adolescent
  • Adult
  • Aged
  • Anastomosis, Surgical
  • Female
  • Follow-Up Studies
  • Health Care Costs
  • Humans
  • Incidence
  • Kidney Transplantation
  • Male
  • Middle Aged
  • Prospective Studies
  • Stents
  • Ureter
  • Urinary Bladder
  • Urologic Diseases
  • Journal Article
  • Randomized Controlled Trial
  • Cost-benefit analysis
  • Postoperative complications

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