Impact of Using Conventional Inlet/Outlet Boundary Conditions on Haemodynamic Metrics in a Subject-Specific Rabbit Aorta

Michael McElroy, Amir Keshmiri

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Computational fluid dynamics is a tool capable of accurately measuring metrics currently used to predict the behaviour of cardiovascular diseases. This study quantifies the impact various commonly used inlet and outlet boundary conditions have on various shear rate–based haemodynamic metrics currently used for predicting the localisation of cardiovascular diseases. Simulations are conducted on an accurately represented rabbit aorta configuration and comparison has been made against available in vivo data. The boundary conditions studied include two different inlet profiles, three outlet boundary conditions, and steady-state versus pulsatile flow cases. Large variations were found in the results, particularly when using different outlet boundary conditions, and the discrepancies were evaluated both quantitatively and qualitatively. The results clearly highlight the importance of the type of boundary condition used when simulating complex cardiovascular models. By restricting the attention to the flow withi...
    Original languageEnglish
    Pages (from-to)103-113
    Number of pages11
    JournalProceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
    Volume232
    Issue number2
    Early online date25 Mar 2017
    DOIs
    Publication statusPublished - 1 Feb 2018

    Keywords

    • Aortic lesion
    • boundary conditions
    • cardiovascular disease
    • computational fluid dynamics
    • haemodynamic metrics
    • rabbit aorta
    • wall shear stress

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