TY - JOUR
T1 - Impaired quality of life and sexual function in overweight and obese men: The European male ageing study
AU - Han, Thang S.
AU - Tajar, Abdelouahid
AU - O'Neill, Terence W.
AU - Jiang, Min
AU - Bartfai, György
AU - Boonen, Steven
AU - Casanueva, Felipe F.
AU - Finn, Joseph D.
AU - Forti, Gianni
AU - Giwercman, Aleksander
AU - Huhtaniemi, Ilpo T.
AU - Kula, Krzysztof
AU - Pendleton, Neil
AU - Punab, Margus
AU - Silman, Alan J.
AU - Vanderschueren, Dirk
AU - Lean, Michael E J
AU - Wu, Frederick C W
AU - Petrone, Luisa
AU - Corona, Giovanni
AU - Borghs, Herman
AU - Slowikowska-Hilczer, Jolanta
AU - Walczak-Jedrzejowska, Renata
AU - Steer, Philip
AU - Lee, David
AU - Pye, Stephen
AU - Lage, Mary
AU - Földesi, Imre
AU - Fejes, Imre
AU - Korrovitz, Paul
PY - 2011/6
Y1 - 2011/6
N2 - Background: Few published data link overweight and obesity with measures of quality of life (QoL) including sexual health in men. Objective: To assess the association of overweight/obesity with impairment of physical and psychological QoL and sexual functions in men. Design and setting: Cross-sectional, multicentre survey of 3369 community-dwelling men aged 40-79 (mean ± S.D., 60 ± 11) years randomly selected from eight European centres. Outcomes: Adiposity was assessed by body mass index (BMI) and waist circumference (WC), QoL and functional impairments by physical andpsychological functiondomains of the Short Form-36 questionnaire, Beck's Depression Inventory and the European Male Ageing Study sexual function questionnaire. Results: Complete data on sexual activities and erectile function were available in 2734 (92%) and 3193 (95%) of the participants respectively. From the population studied, 814 men were obese (BMI ≥ 30 kg/m2) and 1171 had WC ≥ 102 cm, 25% of all men were unable to do vigorous activity and 2-13% reported depressive symptoms. Symptoms of sexual dysfunction ranged between 22% (low sexual desire) and 40% (infrequent morning erections) of the participants. Among obese men with both BMI ≥ 30 kg/m2 and WC ≥ 102 cm, at least one symptom of impaired physical, psychological and sexual function was reported by 41, 43 and 73% of the participants respectively. Compared with the reference group of non-obese men (BMI <30 kg/m2 and WC <102 cm), men with BMI ≥ 30 kg/m2 and WC ≥ 102 cm more frequently reported at least one symptom of impaired physical function (odds ratio (OR)=2.67; confidence interval (CI): 2.07-3.45, P <0.001), impaired psychological function (OR=1.48; CI: 1.14-1.90, P <0.01) and impaired sexual function (OR=1.45; CI: 1.14-1.85, P <0.01). These functional impairments were also more prevalent in men who had WC ≥ 102 cm even with BMI <30 kg/m 2, but those with BMI ≥ 30 kg/m2 and WC <102 cm generally did not suffer from increased impaired physical or sexual health. Men with high BMI and WC were at even greater likelihood of having a composite of two or more or three or more symptoms compared with those with normal BMI and WC. Conclusions: Men with high WC, including those who are 'non-obese' with BMI <30 kg/m2, have poor QoL with symptoms of impaired physical, psychological and sexual functions. Health promotion to improve QoL should focus on prevention of obesity and central fat accumulation. © 2011 European Society of Endocrinology.
AB - Background: Few published data link overweight and obesity with measures of quality of life (QoL) including sexual health in men. Objective: To assess the association of overweight/obesity with impairment of physical and psychological QoL and sexual functions in men. Design and setting: Cross-sectional, multicentre survey of 3369 community-dwelling men aged 40-79 (mean ± S.D., 60 ± 11) years randomly selected from eight European centres. Outcomes: Adiposity was assessed by body mass index (BMI) and waist circumference (WC), QoL and functional impairments by physical andpsychological functiondomains of the Short Form-36 questionnaire, Beck's Depression Inventory and the European Male Ageing Study sexual function questionnaire. Results: Complete data on sexual activities and erectile function were available in 2734 (92%) and 3193 (95%) of the participants respectively. From the population studied, 814 men were obese (BMI ≥ 30 kg/m2) and 1171 had WC ≥ 102 cm, 25% of all men were unable to do vigorous activity and 2-13% reported depressive symptoms. Symptoms of sexual dysfunction ranged between 22% (low sexual desire) and 40% (infrequent morning erections) of the participants. Among obese men with both BMI ≥ 30 kg/m2 and WC ≥ 102 cm, at least one symptom of impaired physical, psychological and sexual function was reported by 41, 43 and 73% of the participants respectively. Compared with the reference group of non-obese men (BMI <30 kg/m2 and WC <102 cm), men with BMI ≥ 30 kg/m2 and WC ≥ 102 cm more frequently reported at least one symptom of impaired physical function (odds ratio (OR)=2.67; confidence interval (CI): 2.07-3.45, P <0.001), impaired psychological function (OR=1.48; CI: 1.14-1.90, P <0.01) and impaired sexual function (OR=1.45; CI: 1.14-1.85, P <0.01). These functional impairments were also more prevalent in men who had WC ≥ 102 cm even with BMI <30 kg/m 2, but those with BMI ≥ 30 kg/m2 and WC <102 cm generally did not suffer from increased impaired physical or sexual health. Men with high BMI and WC were at even greater likelihood of having a composite of two or more or three or more symptoms compared with those with normal BMI and WC. Conclusions: Men with high WC, including those who are 'non-obese' with BMI <30 kg/m2, have poor QoL with symptoms of impaired physical, psychological and sexual functions. Health promotion to improve QoL should focus on prevention of obesity and central fat accumulation. © 2011 European Society of Endocrinology.
U2 - 10.1530/EJE-10-1129
DO - 10.1530/EJE-10-1129
M3 - Article
C2 - 21459980
SN - 0804-4643
VL - 164
SP - 1003
EP - 1011
JO - European Journal of Endocrinology
JF - European Journal of Endocrinology
IS - 6
ER -
