In-beam PET imaging for the control of heavy-ion tumour therapy

J. Pawelke, W. Enghardt, Th Haberer, B. G. Hasch, R. Hinz, M. Krämer, K. Lauckner, M. Sobiella

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A method for the in-situ control of the heavy-ion tumour therapy by means of positron emission tomography is introduced. This method is founded on the measurement of the dynamic spatial distributions of β+-emitters generated by nuclear fragmentation during the irradiation and their relation to the dose. In order to study this relationship and to derive the dose distribution from the measured β+-activity distribution, a framework of model calculations is used. Results of phantom experiments with 12C ion beams will be presented, demonstrating good agreement between experiment and calculation as well as the possibilities and limits of the PET-technique for treatment plan verification and beam monitoring. © 1997 IEEE.
    Original languageEnglish
    Pages (from-to)1492-1498
    Number of pages6
    JournalIeee Transactions on Nuclear Science
    Volume44
    Issue number4
    DOIs
    Publication statusPublished - 1997

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