TY - JOUR
T1 - In vitro activities of terbinafine against Aspergillus species in comparison with those of itraconazole and amphotericin B
AU - Moore, Caroline B.
AU - Walls, Caroline M.
AU - Denning, David W.
PY - 2001/6/1
Y1 - 2001/6/1
N2 - Compared with the in vitro activities of itraconazole (geometric mean MIC [GM], 0.56 μg/ml) and amphotericin B (GM, 0.66 μg/ml), the in vitro activity of terbinafine was inferior against Aspergillus fumigatus (GM, 19.03 μg/ml) (P < 0.05) and superior against A. flavus (GM, 0.10 μg/ml), A. terreus (GM, 0.16 μg/ml), and A. niger (GM, 0.19 μg/ml). Clinical correlation is required, as trailing endpoints are problematic.
AB - Compared with the in vitro activities of itraconazole (geometric mean MIC [GM], 0.56 μg/ml) and amphotericin B (GM, 0.66 μg/ml), the in vitro activity of terbinafine was inferior against Aspergillus fumigatus (GM, 19.03 μg/ml) (P < 0.05) and superior against A. flavus (GM, 0.10 μg/ml), A. terreus (GM, 0.16 μg/ml), and A. niger (GM, 0.19 μg/ml). Clinical correlation is required, as trailing endpoints are problematic.
UR - http://www.scopus.com/inward/record.url?scp=0035018492&partnerID=8YFLogxK
U2 - 10.1128/AAC.45.6.1882-1885.2001
DO - 10.1128/AAC.45.6.1882-1885.2001
M3 - Article
C2 - 11353643
AN - SCOPUS:0035018492
SN - 0066-4804
VL - 45
SP - 1882
EP - 1885
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 6
ER -