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In vitro susceptibilities of zygomycetes to combinations of antimicrobial agents

  • Eurofung Network
  • Radbond Institute for Health Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Combinations of antimicrobial agents were tested against 35 strains of zygomycetes. The interaction between amphotericin B and rifampin was synergistic or additive. Flucytosine alone was inactive and, upon combination with amphotericin B, synergy was not achieved. The combination of amphotericin B with terbinafine was synergistic for 20% of strains, and the interaction between terbinafine and voriconazole was synergistic for 44% of strains. Antagonism was not observed.

Original languageEnglish
Pages (from-to)2708-2711
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume46
Issue number8
DOIs
Publication statusPublished - 1 Jan 2002

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