In vivo demonstration of FNR dimers in response to lower O2 availability

Adrian J. Jervis, Jeffrey Green

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Escherichia coli FNR is an O2-sensing transcription factor. In vitro studies indicate that anaerobic iron-sulfur cluster acquisition promotes FNR dimerization. Here, two-hybrid assays show that iron-sulfur cluster-dependent FNR dimers are formed in vivo in response to lower O 2 availability, consistent with the current model of FNR activation. Copyright © 2007, American Society for Microbiology. All Rights Reserved.
    Original languageEnglish
    Pages (from-to)2930-2932
    Number of pages2
    JournalJournal of Bacteriology
    Volume189
    Issue number7
    DOIs
    Publication statusPublished - Apr 2007

    Research Beacons, Institutes and Platforms

    • Manchester Institute of Biotechnology

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