In vivo imaging of cortical vitreous using 1050-nm swept source deep range imaging optical coherence tomography

Purpose: To determine the prevalence of the Bursa Premacularis and Space of Martegiani, and to measure the dimensions of the Bursa using the new 1,050nm Swept-Source Deep Range Imaging Optical Coherence Tomography (DRI-OCT1 Atlantis®). Design: Retrospective cross-sectional study. Methods: One hundred and nineteen consecutive patients (5-100 years) underwent DRI-OCT1 Atlantis®. The prevalence of the Bursa Premacularis and Space of Martegiani and the stage of posterior vitreous detachment (PVD) was determined. The horizontal (width) and anteroposterior (depth) dimensions of the Bursa were recorded along with the patient’s age. Results: A Bursa was detected in 57.1% (136/238) of eyes. The Bursa and Space of Martegiani coexisted in 97.8% of eyes. Prevalence of detected Bursa was 84.5% in eyes with either no PVD or perifoveal PVD only; the prevalence fell with further increases in the extent of PVD. Prevalence of detected Bursa was 75.4% in patient group aged 0-60 years and 38% in the group aged 60-100 years. Mean width was 7,001µm (range: 3,354–10,316µm, SD: 1412µm) and mean depth was 416µm (range: 31-1,189µm, SD: 187µm). Width and depth of the Bursa did not correlate with age (R2 Width=0.0316; R2 Depth=0.0108). Bilateral Bursa tended to be symmetrical in width but less so in depth (R2 Width=0.63 p