Incidence and natural history of challenge-proven cow's milk allergy in European children--EuroPrevall birth cohort.

A A Schoemaker; A B Sprikkelman; K E Grimshaw; G Roberts; L Grabenhenrich; L Rosenfeld; S Siegert; R Dubakiene; O Rudzeviciene; M Reche; A Fiandor; N G Papadopoulos; A Malamitsi-Puchner; A Fiocchi; L Dahdah; S Th Sigurdardottir; M Clausen; A Stańczyk-Przyłuska; K Zeman; E N C Mills; D McBride; T Keil; K Beyer

doi:10.1111/all.12630

Incidence and natural history of challenge-proven cow's milk allergy in European children--EuroPrevall birth cohort.

A A Schoemaker, A B Sprikkelman, K E Grimshaw, G Roberts, L Grabenhenrich, L Rosenfeld, S Siegert, R Dubakiene, O Rudzeviciene, M Reche, A Fiandor, N G Papadopoulos, A Malamitsi-Puchner, A Fiocchi, L Dahdah, S Th Sigurdardottir, M Clausen, A Stańczyk-Przyłuska, K Zeman, E N C MillsD McBride, T Keil, K Beyer

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Abstract

BACKGROUND: Cow's milk allergy (CMA) is one of the most commonly reported childhood food problems. Community-based incidence and prevalence estimates vary widely, due to possible misinterpretations of presumed reactions to milk and differences in study design, particularly diagnostic criteria. METHODS: Children from the EuroPrevall birth cohort in 9 European countries with symptoms possibly related to CMA were invited for clinical evaluation including cows' milk-specific IgE antibodies (IgE), skin prick test (SPT) reactivity and double-blind, placebo-controlled food challenge. RESULTS: Across Europe, 12 049 children were enrolled, and 9336 (77.5%) were followed up to 2 years of age. CMA was suspected in 358 children and confirmed in 55 resulting in an overall incidence of challenge-proven CMA of 0.54% (95% CI 0.41-0.70). National incidences ranged from 1% (in the Netherlands and UK) to

Original language	English
Journal	Allergy
Volume	70
Issue number	8
DOIs	https://doi.org/10.1111/all.12630
Publication status	Published - Aug 2015

Keywords

EuroPrevall
birth cohort study
cow's milk allergy
food allergy
incidence

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10.1111/all.12630

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Schoemaker, A. A., Sprikkelman, A. B., Grimshaw, K. E., Roberts, G., Grabenhenrich, L., Rosenfeld, L., Siegert, S., Dubakiene, R., Rudzeviciene, O., Reche, M., Fiandor, A., Papadopoulos, N. G., Malamitsi-Puchner, A., Fiocchi, A., Dahdah, L., Sigurdardottir, S. T., Clausen, M., Stańczyk-Przyłuska, A., Zeman, K., ... Beyer, K. (2015). Incidence and natural history of challenge-proven cow's milk allergy in European children--EuroPrevall birth cohort. Allergy, 70(8). https://doi.org/10.1111/all.12630

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title = "Incidence and natural history of challenge-proven cow's milk allergy in European children--EuroPrevall birth cohort.",

abstract = "BACKGROUND: Cow's milk allergy (CMA) is one of the most commonly reported childhood food problems. Community-based incidence and prevalence estimates vary widely, due to possible misinterpretations of presumed reactions to milk and differences in study design, particularly diagnostic criteria. METHODS: Children from the EuroPrevall birth cohort in 9 European countries with symptoms possibly related to CMA were invited for clinical evaluation including cows' milk-specific IgE antibodies (IgE), skin prick test (SPT) reactivity and double-blind, placebo-controlled food challenge. RESULTS: Across Europe, 12 049 children were enrolled, and 9336 (77.5%) were followed up to 2 years of age. CMA was suspected in 358 children and confirmed in 55 resulting in an overall incidence of challenge-proven CMA of 0.54% (95% CI 0.41-0.70). National incidences ranged from 1% (in the Netherlands and UK) to",

keywords = "EuroPrevall, birth cohort study, cow's milk allergy, food allergy, incidence",

author = "Schoemaker, {A A} and Sprikkelman, {A B} and Grimshaw, {K E} and G Roberts and L Grabenhenrich and L Rosenfeld and S Siegert and R Dubakiene and O Rudzeviciene and M Reche and A Fiandor and Papadopoulos, {N G} and A Malamitsi-Puchner and A Fiocchi and L Dahdah and Sigurdardottir, {S Th} and M Clausen and A Sta{\'n}czyk-Przy{\l}uska and K Zeman and Mills, {E N C} and D McBride and T Keil and K Beyer",

year = "2015",

month = aug,

doi = "10.1111/all.12630",

language = "English",

volume = "70",

journal = "Allergy",

issn = "0105-4538",

publisher = "John Wiley & Sons Ltd",

number = "8",

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Schoemaker, AA, Sprikkelman, AB, Grimshaw, KE, Roberts, G, Grabenhenrich, L, Rosenfeld, L, Siegert, S, Dubakiene, R, Rudzeviciene, O, Reche, M, Fiandor, A, Papadopoulos, NG, Malamitsi-Puchner, A, Fiocchi, A, Dahdah, L, Sigurdardottir, ST, Clausen, M, Stańczyk-Przyłuska, A, Zeman, K, Mills, ENC, McBride, D, Keil, T & Beyer, K 2015, 'Incidence and natural history of challenge-proven cow's milk allergy in European children--EuroPrevall birth cohort.', Allergy, vol. 70, no. 8. https://doi.org/10.1111/all.12630

TY - JOUR

T1 - Incidence and natural history of challenge-proven cow's milk allergy in European children--EuroPrevall birth cohort.

AU - Schoemaker, A A

AU - Sprikkelman, A B

AU - Grimshaw, K E

AU - Roberts, G

AU - Grabenhenrich, L

AU - Rosenfeld, L

AU - Siegert, S

AU - Dubakiene, R

AU - Rudzeviciene, O

AU - Reche, M

AU - Fiandor, A

AU - Papadopoulos, N G

AU - Malamitsi-Puchner, A

AU - Fiocchi, A

AU - Dahdah, L

AU - Sigurdardottir, S Th

AU - Clausen, M

AU - Stańczyk-Przyłuska, A

AU - Zeman, K

AU - Mills, E N C

AU - McBride, D

AU - Keil, T

AU - Beyer, K

PY - 2015/8

Y1 - 2015/8

N2 - BACKGROUND: Cow's milk allergy (CMA) is one of the most commonly reported childhood food problems. Community-based incidence and prevalence estimates vary widely, due to possible misinterpretations of presumed reactions to milk and differences in study design, particularly diagnostic criteria. METHODS: Children from the EuroPrevall birth cohort in 9 European countries with symptoms possibly related to CMA were invited for clinical evaluation including cows' milk-specific IgE antibodies (IgE), skin prick test (SPT) reactivity and double-blind, placebo-controlled food challenge. RESULTS: Across Europe, 12 049 children were enrolled, and 9336 (77.5%) were followed up to 2 years of age. CMA was suspected in 358 children and confirmed in 55 resulting in an overall incidence of challenge-proven CMA of 0.54% (95% CI 0.41-0.70). National incidences ranged from 1% (in the Netherlands and UK) to

AB - BACKGROUND: Cow's milk allergy (CMA) is one of the most commonly reported childhood food problems. Community-based incidence and prevalence estimates vary widely, due to possible misinterpretations of presumed reactions to milk and differences in study design, particularly diagnostic criteria. METHODS: Children from the EuroPrevall birth cohort in 9 European countries with symptoms possibly related to CMA were invited for clinical evaluation including cows' milk-specific IgE antibodies (IgE), skin prick test (SPT) reactivity and double-blind, placebo-controlled food challenge. RESULTS: Across Europe, 12 049 children were enrolled, and 9336 (77.5%) were followed up to 2 years of age. CMA was suspected in 358 children and confirmed in 55 resulting in an overall incidence of challenge-proven CMA of 0.54% (95% CI 0.41-0.70). National incidences ranged from 1% (in the Netherlands and UK) to

KW - EuroPrevall

KW - birth cohort study

KW - cow's milk allergy

KW - food allergy

KW - incidence

U2 - 10.1111/all.12630

DO - 10.1111/all.12630

M3 - Article

C2 - 25864712

SN - 0105-4538

VL - 70

JO - Allergy

JF - Allergy

IS - 8

ER -

Incidence and natural history of challenge-proven cow's milk allergy in European children--EuroPrevall birth cohort.

Abstract

Keywords

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