Increasing age at symptom onset is associated with worse radiological damage at presentation in patients with early inflammatory polyarthritis

Marwan Bukhari, Mark Lunt, Anne Barton, Dianne Bunn, Alan Silman, Deborah Symmons

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Increasing age at onset has been associated with worse outcome in rheumatoid arthritis, although there are few data from unselected inception cohorts. Hypothesis: Increasing age is associated with a higher risk of erosions at presentation, and this increase is not explained by age-related disease confounders. Subjects and methods: 222 subjects (median onset age 59 years) were studied from a primary-care-based register of new-onset inflammatory polyarthritis. Patients had hand and feet radiographs taken within 12 months from symptom onset. Films were scored by two readers using the Larsen score. The risk of erosions in those aged 50-69 and ≥70 years at onset was compared with the risk in those aged
Original languageEnglish
Pages (from-to)389-393
Number of pages4
JournalAnnals of the rheumatic diseases
Volume66
Issue number3
DOIs
Publication statusPublished - Mar 2007

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