Indexing aortic valve area by body surface area increases the prevalence of severe aortic stenosis

Nikolaus Jander, Christa Gohlke-Bärwolf, Edda Bahlmann, Eva Gerdts, Kurt Boman, John B. Chambers, Kenneth Egstrup, Christoph A. Nienaber, Terje R. Pedersen, Simon Ray, Anne B. Rossebø, Ronnie Willenheimer, Rolf Peter Kienzle, Kristian Wachtell, Franz Josef Neumann, Jan Minners

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background To account for differences in body size in patients with aortic stenosis, aortic valve area (AVA) is divided by body surface area (BSA) to calculate indexed AVA (AVAindex). Cut-off values for severe stenosis are 2.5 m/s) and from 1525 patients prospectively followed in the simvastatin and ezetimibe in aortic stenosis (SEAS) trial were analysed. Results The prevalence of severe stenosis increased with the AVAindex criterion compared to AVA from 71% to 80% in the retrospective cohort, and from 29% to 44% in SEAS (both p
    Original languageEnglish
    Pages (from-to)28-33
    Number of pages5
    JournalHeart
    Volume100
    Issue number1
    DOIs
    Publication statusPublished - Jan 2014

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