Inflammatory BCG adenitis associated with immune reconstitution following allogeneic haematopoietic stem cell transplant in infancy

E Searle; H Patel; FJ Vilar; M Gharib; AJ Turner; G Batra; RF Wynn

doi:10.1002/pbc.22143

Inflammatory BCG adenitis associated with immune reconstitution following allogeneic haematopoietic stem cell transplant in infancy

E Searle, H Patel, FJ Vilar, M Gharib, AJ Turner, G Batra, RF Wynn

Division of Cell Matrix Biology & Regenerative Medicine (L5)

Research output: Contribution to journal › Article › peer-review

Abstract

We describe four cases of a localized, granulomatous reaction to BCG including ipsilateral painful, suppurative lymphadenopathy associated with donor immune reconstitution following allogeneic haematopoietic stem cell transplant performed in infancy and preceded by uneventful, routine BCG immunisation. The management of the inflammatory disease in these cases with surgery, antimycobacterial chemotherapy and steroids, is discussed.

Original language	English
Pages (from-to)	166-169
Number of pages	4
Journal	Pediatric blood \& cancer
Volume	54
Issue number	1
DOIs	https://doi.org/10.1002/pbc.22143
Publication status	Published - 2009

Keywords

BCG
immune reconstitution
transplant

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10.1002/pbc.22143

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title = "Inflammatory BCG adenitis associated with immune reconstitution following allogeneic haematopoietic stem cell transplant in infancy",

abstract = "We describe four cases of a localized, granulomatous reaction to BCG including ipsilateral painful, suppurative lymphadenopathy associated with donor immune reconstitution following allogeneic haematopoietic stem cell transplant performed in infancy and preceded by uneventful, routine BCG immunisation. The management of the inflammatory disease in these cases with surgery, antimycobacterial chemotherapy and steroids, is discussed.",

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author = "E Searle and H Patel and FJ Vilar and M Gharib and AJ Turner and G Batra and RF Wynn",

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AU - Searle, E

AU - Patel, H

AU - Vilar, FJ

AU - Gharib, M

AU - Turner, AJ

AU - Batra, G

AU - Wynn, RF

PY - 2009

Y1 - 2009

N2 - We describe four cases of a localized, granulomatous reaction to BCG including ipsilateral painful, suppurative lymphadenopathy associated with donor immune reconstitution following allogeneic haematopoietic stem cell transplant performed in infancy and preceded by uneventful, routine BCG immunisation. The management of the inflammatory disease in these cases with surgery, antimycobacterial chemotherapy and steroids, is discussed.

AB - We describe four cases of a localized, granulomatous reaction to BCG including ipsilateral painful, suppurative lymphadenopathy associated with donor immune reconstitution following allogeneic haematopoietic stem cell transplant performed in infancy and preceded by uneventful, routine BCG immunisation. The management of the inflammatory disease in these cases with surgery, antimycobacterial chemotherapy and steroids, is discussed.

KW - BCG

KW - immune reconstitution

KW - transplant

U2 - 10.1002/pbc.22143

DO - 10.1002/pbc.22143

M3 - Article

SN - 1545-5017

VL - 54

SP - 166

EP - 169

JO - Pediatric blood \& cancer

JF - Pediatric blood \& cancer

IS - 1

ER -

Inflammatory BCG adenitis associated with immune reconstitution following allogeneic haematopoietic stem cell transplant in infancy

Abstract

Keywords

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