TY - GEN
T1 - Influence of geometric variations on LV activation times
T2 - 1st International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2010 and Cardiac Electrophysiological Simulation Challenge, CESC 2010 - Held in Conjunction with MICCAI 2010
AU - Hoogendoorn, Corné
AU - Pashaei, Ali
AU - Sebastián, Rafael
AU - Sukno, Federico M.
AU - Cámara, Oscar
AU - Frangi, Alejandro F.
PY - 2010
Y1 - 2010
N2 - We present the fully automated pipeline we have developed to obtain electrophysiological simulations of the heart on a large atlasbased virtual population. This virtual population was generated from a statistical model of left ventricular geometry, represented by a surface model. Correspondence between tetrahedralized volumetric meshes was obtained using Thin Plate Spline warps. Simulations are based on the fast solving of Eikonal equations, and stimulation sites correspond to physiological activation. We report variations of total activation time introduced by geometry, as well as variations in the location of last activation. The obtained results suggest that the total activation time has a strong dependence on LV geometrical variation such as dilation-tohypertrophy.
AB - We present the fully automated pipeline we have developed to obtain electrophysiological simulations of the heart on a large atlasbased virtual population. This virtual population was generated from a statistical model of left ventricular geometry, represented by a surface model. Correspondence between tetrahedralized volumetric meshes was obtained using Thin Plate Spline warps. Simulations are based on the fast solving of Eikonal equations, and stimulation sites correspond to physiological activation. We report variations of total activation time introduced by geometry, as well as variations in the location of last activation. The obtained results suggest that the total activation time has a strong dependence on LV geometrical variation such as dilation-tohypertrophy.
UR - http://www.scopus.com/inward/record.url?scp=78049378468&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-15835-3_25
DO - 10.1007/978-3-642-15835-3_25
M3 - Conference contribution
AN - SCOPUS:78049378468
SN - 364215834X
SN - 9783642158346
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 242
EP - 251
BT - STACOM 2010
Y2 - 20 September 2010 through 20 September 2010
ER -