Influence of Hydroxyapatite on Extruded 3D Scaffolds

Paulo Jorge Da Silva bartolo; Geraldine Rodriguez; Juliana Dias; Marcos Akira d?????vila; Paulo B??rtolo

doi:10.1016/j.proeng.2013.05.120

Influence of Hydroxyapatite on Extruded 3D Scaffolds

Paulo Jorge Da Silva bartolo, Geraldine Rodriguez, Juliana Dias, Marcos Akira d?????vila, Paulo B??rtolo

Research output: Contribution to journal › Article › peer-review

Abstract

Ideal scaffolds for tissue engineering must mimic the complex characteristics of natural tissues and their mechanical performance. In this work, Polycaprolactone (PCL) and composite Polycaprolactone/Hydroxyapatite (PCL/HA) (75/25) scaffolds were produced by using an extrusion-based process called BioExtruder. The structures were characterized regarding the chemical, thermal, morphological and mechanical properties, in order to investigate the effect of HA addition in the polymeric scaffolds. Results show that the incorporation of HA in the 3D structures improve both the thermal and mechanical properties.

Original language	English
Pages (from-to)	263-269
Number of pages	7
Journal	Procedia Engineering
Volume	59
DOIs	https://doi.org/10.1016/j.proeng.2013.05.120
Publication status	Published - 2013

Keywords

Extrusion.
Hydroxyapatite
Polycaprolactone
scaffold
tissue engineering

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10.1016/j.proeng.2013.05.120

http://www.sciencedirect.com/science/article/pii/S1877705813010345

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title = "Influence of Hydroxyapatite on Extruded 3D Scaffolds",

abstract = "Ideal scaffolds for tissue engineering must mimic the complex characteristics of natural tissues and their mechanical performance. In this work, Polycaprolactone (PCL) and composite Polycaprolactone/Hydroxyapatite (PCL/HA) (75/25) scaffolds were produced by using an extrusion-based process called BioExtruder. The structures were characterized regarding the chemical, thermal, morphological and mechanical properties, in order to investigate the effect of HA addition in the polymeric scaffolds. Results show that the incorporation of HA in the 3D structures improve both the thermal and mechanical properties.",

keywords = "Extrusion., Hydroxyapatite, Polycaprolactone, scaffold, tissue engineering",

author = "{Da Silva bartolo}, {Paulo Jorge} and Geraldine Rodriguez and Juliana Dias and d?????vila, {Marcos Akira} and Paulo B??rtolo",

year = "2013",

doi = "10.1016/j.proeng.2013.05.120",

language = "English",

volume = "59",

pages = "263--269",

journal = "Procedia Engineering",

issn = "1877-7058",

publisher = "Elsevier BV",

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TY - JOUR

T1 - Influence of Hydroxyapatite on Extruded 3D Scaffolds

AU - Da Silva bartolo, Paulo Jorge

AU - Rodriguez, Geraldine

AU - Dias, Juliana

AU - d?????vila, Marcos Akira

AU - B??rtolo, Paulo

PY - 2013

Y1 - 2013

N2 - Ideal scaffolds for tissue engineering must mimic the complex characteristics of natural tissues and their mechanical performance. In this work, Polycaprolactone (PCL) and composite Polycaprolactone/Hydroxyapatite (PCL/HA) (75/25) scaffolds were produced by using an extrusion-based process called BioExtruder. The structures were characterized regarding the chemical, thermal, morphological and mechanical properties, in order to investigate the effect of HA addition in the polymeric scaffolds. Results show that the incorporation of HA in the 3D structures improve both the thermal and mechanical properties.

AB - Ideal scaffolds for tissue engineering must mimic the complex characteristics of natural tissues and their mechanical performance. In this work, Polycaprolactone (PCL) and composite Polycaprolactone/Hydroxyapatite (PCL/HA) (75/25) scaffolds were produced by using an extrusion-based process called BioExtruder. The structures were characterized regarding the chemical, thermal, morphological and mechanical properties, in order to investigate the effect of HA addition in the polymeric scaffolds. Results show that the incorporation of HA in the 3D structures improve both the thermal and mechanical properties.

KW - Extrusion.

KW - Hydroxyapatite

KW - Polycaprolactone

KW - scaffold

KW - tissue engineering

U2 - 10.1016/j.proeng.2013.05.120

DO - 10.1016/j.proeng.2013.05.120

M3 - Article

SN - 1877-7058

VL - 59

SP - 263

EP - 269

JO - Procedia Engineering

JF - Procedia Engineering

ER -

Influence of Hydroxyapatite on Extruded 3D Scaffolds

Abstract

Keywords

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