TY - JOUR
T1 - Influence of lifestyle factors on quantitative heel ultrasound measurements in middle-aged and elderly men
AU - Pye, Stephen R.
AU - Devakumar, Vinodh
AU - Boonen, Steven
AU - Borghs, Herman
AU - Vanderschueren, Dirk
AU - Adams, Judith E.
AU - Ward, Kate A.
AU - Bartfai, Gyorgy
AU - Casanueva, Felipe F.
AU - Finn, Joseph D.
AU - Forti, Gianni
AU - Giwercman, Aleksander
AU - Han, Thang S.
AU - Huhtaniemi, Ilpo T.
AU - Kula, Krzysztof
AU - Lean, Michael E J
AU - Pendleton, Neil
AU - Punab, Margus
AU - Silman, Alan J.
AU - Wu, Frederick C W
AU - O'Neill, Terence W.
PY - 2010/3
Y1 - 2010/3
N2 - We examined the distribution of quantitative heel ultrasound (QUS) parameters in population samples of European men and looked at the influence of lifestyle factors on the occurrence of these parameters. Men aged between 40 and 79 years were recruited from eight European centers and invited to attend for an interviewer-assisted questionnaire, assessment of physical performance, and quantitative ultrasound (QUS) of the calcaneus (Hologic; Sahara). The relationships between QUS parameters and lifestyle variables were assessed using linear regression with adjustments for age, center, and weight. Three thousand two hundred fiftyeight men, mean age 60.0 years, were included in the analysis. A higher PASE score (upper vs. lower tertile) was associated with a higher BUA (β coefficient = 2.44 dB/ Mhz), SOS (β = 6.83 m/s), and QUI (β = 3.87). Compared to those who were inactive, those who walked or cycled more than an hour per day had a higher BUA (β = 3.71 dB/Mhz), SOS (β = 6.97 m/s), and QUI (β = 4.50). A longer time to walk 50 ft was linked with a lower BUA (β = -0.62 dB/ Mhz), SOS (β = -1.06 m/s), and QUI (β = -0.69). Smoking was associated with a reduction in BUA, SOS, and QUI. There was a U-shaped association with frequency of alcohol consumption. Modification of lifestyle, including increasing physical activity and stopping smoking, may help optimize bone strength and reduce the risk of fracture in middle-aged and elderly European men. © 2010 Springer Science+Business Media, LLC.
AB - We examined the distribution of quantitative heel ultrasound (QUS) parameters in population samples of European men and looked at the influence of lifestyle factors on the occurrence of these parameters. Men aged between 40 and 79 years were recruited from eight European centers and invited to attend for an interviewer-assisted questionnaire, assessment of physical performance, and quantitative ultrasound (QUS) of the calcaneus (Hologic; Sahara). The relationships between QUS parameters and lifestyle variables were assessed using linear regression with adjustments for age, center, and weight. Three thousand two hundred fiftyeight men, mean age 60.0 years, were included in the analysis. A higher PASE score (upper vs. lower tertile) was associated with a higher BUA (β coefficient = 2.44 dB/ Mhz), SOS (β = 6.83 m/s), and QUI (β = 3.87). Compared to those who were inactive, those who walked or cycled more than an hour per day had a higher BUA (β = 3.71 dB/Mhz), SOS (β = 6.97 m/s), and QUI (β = 4.50). A longer time to walk 50 ft was linked with a lower BUA (β = -0.62 dB/ Mhz), SOS (β = -1.06 m/s), and QUI (β = -0.69). Smoking was associated with a reduction in BUA, SOS, and QUI. There was a U-shaped association with frequency of alcohol consumption. Modification of lifestyle, including increasing physical activity and stopping smoking, may help optimize bone strength and reduce the risk of fracture in middle-aged and elderly European men. © 2010 Springer Science+Business Media, LLC.
KW - Bone mineral density
KW - Epidemiology
KW - Exercise
KW - Risk factors
KW - Ultrasound
U2 - 10.1007/s00223-009-9330-y
DO - 10.1007/s00223-009-9330-y
M3 - Article
C2 - 20084503
SN - 1432-0827
VL - 86
SP - 211
EP - 219
JO - Calcified tissue international
JF - Calcified tissue international
IS - 3
ER -