Initial observations using a novel "cine" magnetic resonance imaging technique to detect changes in abdominal motion caused by encapsulating peritoneal sclerosis

Benjamin Wright, Angela Summers, John Fenner, Richard Gillott, Charles E. Hutchinson, Paul A. Spencer, Martin Wilkie, Helen Hurst, Sarah Herrick, Paul Brenchley, Titus Augustine, Karna D. Bardhan

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Encapsulating peritoneal sclerosis (EPS) is an uncommon complication of peritoneal dialysis (PD), with high mortality and morbidity. The peritoneum thickens, dysfunctions, and forms a cocoon that progressively "strangulates" the small intestine, causing malnutrition, ischemia, and infarction. There is as yet no reliable noninvasive means of diagnosis, but recent developments in image analysis of cine magnetic resonance imaging for the recognition of adhesions offers a way forward. We used this protocol before surgery in 3 patients with suspected EPS. Image analysis revealed patterns of abdominal movement that were markedly different from the patterns in healthy volunteers. The volunteers showed marked movement throughout the abdomen; in contrast, movement in EPS patients was restricted to just below the diaphragm. This clear difference provides early "proof of principle" of the approach that we have developed. © 2011 International Society for Peritoneal Dialysis.
    Original languageEnglish
    Pages (from-to)287-290
    Number of pages3
    JournalPeritoneal Dialysis International
    Volume31
    Issue number3
    DOIs
    Publication statusPublished - May 2011

    Keywords

    • Cine MRI
    • Encapsulating peritoneal sclerosis

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