Insulin-Like Growth Factor 1 Gene polymorphism and Breast cancer Risk Among Arab Omani Women: A case-control study

Kawthar Al-Ajmi, Shyam S. Ganguly, Adil Al-Ajmi, Zahid Al Mandhari, Mansour S. Al-Moundhri

Research output: Contribution to conferencePaperpeer-review

Abstract

Breast cancer is the most common cancer worldwide with significant global burden. Insulin-like growth factor 1 (IGF1) is an important regulator of cellular growth, differentiation, and apoptosis and mitogenic and antiapoptotic activities. Some studies suggested an association between cytosine adenine (CA) repeats gene polymorphisms of IGF1 and the risk of developing breast cancer while other studies did not find such an association. This study aims investigate the role of IGF1 (CA) repeats gene polymorphisms in the risk of developing breast cancer among Omani women.
Original languageEnglish
Pages103-112
Number of pages8
Publication statusPublished - 2012

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