Integrin-collagen complex: A metal-glutamate handshake

Jordi Bella, Helen M. Berman

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The recently determined crystal structure of the complex between an integrin I domain and a synthetic collagen peptide shows a collagen triple- helix engaged in specific macromolecular recognition and binding. This structure confirms a previously proposed binding mechanism for integrin I domains and has important implications for integrin activation and signalling.
    Original languageEnglish
    Pages (from-to)R121-R126
    JournalStructure
    Volume8
    Issue number6
    DOIs
    Publication statusPublished - 1 Jun 2000

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