Intensity-modulated radiotherapy for lung cancer: Current status and future developments

Clara Chan; Stephanie Lang; Carl Rowbottom; Matthias Guckenberger; Corinne Faivre-Finn; IASLC Advanced Radiation Technology Committee

doi:10.1097/JTO.0000000000000346

Intensity-modulated radiotherapy for lung cancer: Current status and future developments

Clara Chan
, Stephanie Lang
, Carl Rowbottom
, Matthias Guckenberger
, Corinne Faivre-Finn^*
, IASLC Advanced Radiation Technology Committee

^*Corresponding author for this work

Division of Cancer Sciences

Research output: Contribution to journal › Review article › peer-review

Abstract

Radiotherapy plays an important role in the management of lung cancer, with over 50% of patients receiving this modality at some point during their treatment. Intensity-modulated radiotherapy (IMRT) is a technique that adds fluence modulation to beam shaping, which improves radiotherapy dose conformity around the tumor and spares surrounding normal structures. Treatment with IMRT is becoming more widely available for the treatment of lung cancer, despite the paucity of high level evidence supporting the routine use of this more resource intense and complex technique. In this review article, we have summarized data from planning and clinical studies, discussed challenges in implementing IMRT, and made recommendations on the minimum requirements for safe delivery of IMRT.

Original language	English
Pages (from-to)	1598-1608
Number of pages	11
Journal	Journal of Thoracic Oncology
Volume	9
Issue number	11
DOIs	https://doi.org/10.1097/JTO.0000000000000346 https://doi.org/10.1097/JTO.00000000000003462014
Publication status	Published - Nov 2014

Keywords

Dose escalation
Intensity-modulated radiotherapy
Lung cancer
Non-small-cell lung cancer
Radiotherapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Intensity-modulated radiotherapy for lung cancer: Current status and future developments",

abstract = "Radiotherapy plays an important role in the management of lung cancer, with over 50\% of patients receiving this modality at some point during their treatment. Intensity-modulated radiotherapy (IMRT) is a technique that adds fluence modulation to beam shaping, which improves radiotherapy dose conformity around the tumor and spares surrounding normal structures. Treatment with IMRT is becoming more widely available for the treatment of lung cancer, despite the paucity of high level evidence supporting the routine use of this more resource intense and complex technique. In this review article, we have summarized data from planning and clinical studies, discussed challenges in implementing IMRT, and made recommendations on the minimum requirements for safe delivery of IMRT.",

keywords = "Dose escalation, Intensity-modulated radiotherapy, Lung cancer, Non-small-cell lung cancer, Radiotherapy",

author = "Clara Chan and Stephanie Lang and Carl Rowbottom and Matthias Guckenberger and Corinne Faivre-Finn and \{IASLC Advanced Radiation Technology Committee\}",

year = "2014",

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doi = "10.1097/JTO.0000000000000346",

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T1 - Intensity-modulated radiotherapy for lung cancer

T2 - Current status and future developments

AU - Chan, Clara

AU - Lang, Stephanie

AU - Rowbottom, Carl

AU - Guckenberger, Matthias

AU - Faivre-Finn, Corinne

AU - IASLC Advanced Radiation Technology Committee

PY - 2014/11

Y1 - 2014/11

N2 - Radiotherapy plays an important role in the management of lung cancer, with over 50% of patients receiving this modality at some point during their treatment. Intensity-modulated radiotherapy (IMRT) is a technique that adds fluence modulation to beam shaping, which improves radiotherapy dose conformity around the tumor and spares surrounding normal structures. Treatment with IMRT is becoming more widely available for the treatment of lung cancer, despite the paucity of high level evidence supporting the routine use of this more resource intense and complex technique. In this review article, we have summarized data from planning and clinical studies, discussed challenges in implementing IMRT, and made recommendations on the minimum requirements for safe delivery of IMRT.

AB - Radiotherapy plays an important role in the management of lung cancer, with over 50% of patients receiving this modality at some point during their treatment. Intensity-modulated radiotherapy (IMRT) is a technique that adds fluence modulation to beam shaping, which improves radiotherapy dose conformity around the tumor and spares surrounding normal structures. Treatment with IMRT is becoming more widely available for the treatment of lung cancer, despite the paucity of high level evidence supporting the routine use of this more resource intense and complex technique. In this review article, we have summarized data from planning and clinical studies, discussed challenges in implementing IMRT, and made recommendations on the minimum requirements for safe delivery of IMRT.

KW - Dose escalation

KW - Intensity-modulated radiotherapy

KW - Lung cancer

KW - Non-small-cell lung cancer

KW - Radiotherapy

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DO - 10.1097/JTO.0000000000000346

M3 - Review article

C2 - 25436795

SN - 1556-0864

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JO - Journal of Thoracic Oncology

JF - Journal of Thoracic Oncology

IS - 11

ER -

Intensity-modulated radiotherapy for lung cancer: Current status and future developments

Abstract

Keywords

UN SDGs

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