InterPro-an integrated documentation resource for protein families, domains and functional sites

R. Apweiler; T. K. Attwood; A. Bairoch; A. Bateman; E. Birney; M. Biswas; P. Bucher; L. Cerutti; F. Corpet; M. D R Croning; R. Durbin; L. Falquet; W. Fleischman; J. Gouzy; H. Hermjakob; N. Hulo; I. Jonassen; D. Kahn; A. Kanapin; Y. Karavidopoulou; R. Lopez; B. Marx; N. J. Mulder; T. M. Oinn; M. Pagni; F. Servant; C. J A Sigrist; E. M. Zdobnov

doi:10.1093/bioinformatics/16.12.1145

InterPro-an integrated documentation resource for protein families, domains and functional sites

R. Apweiler, T. K. Attwood, A. Bairoch, A. Bateman, E. Birney, M. Biswas, P. Bucher, L. Cerutti, F. Corpet, M. D R Croning, R. Durbin, L. Falquet, W. Fleischman, J. Gouzy, H. Hermjakob, N. Hulo, I. Jonassen, D. Kahn, A. Kanapin, Y. KaravidopoulouR. Lopez, B. Marx, N. J. Mulder, T. M. Oinn, M. Pagni, F. Servant, C. J A Sigrist, E. M. Zdobnov

Research output: Contribution to journal › Article › peer-review

Abstract

Motivation: InterPro is a new integrated documentation resource for protein families, domains and functional sites, developed initially as a means of rationalising the complementary efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Results: Merged annotations from PRINTS, PROSITE and Pfam form the InterPro core. Each combined InterPro entry includes functional descriptions and literature references, and links are made back to the relevant parent database(s), allowing users to see at a glance whether a particular family or domain has associated patterns, profiles, fingerprints, etc. Merged and individual entries (i.e. those that have no counterpart in the companion resources) are assigned unique accession numbers. Release 1.2 of InterPro (June 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification (PTMs) encoded by 6581 different regular expressions, profiles, fingerprints and Hidden Markov Models (HMMs). Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1 000 000 hits from 264 333 different proteins out of 384 572 in SWISS-PROT and TrEMBL.

Original language	English
Pages (from-to)	1145-1150
Number of pages	5
Journal	Bioinformatics
Volume	16
Issue number	12
DOIs	https://doi.org/10.1093/bioinformatics/16.12.1145
Publication status	Published - 2000

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Apweiler, R., Attwood, T. K., Bairoch, A., Bateman, A., Birney, E., Biswas, M., Bucher, P., Cerutti, L., Corpet, F., Croning, M. D. R., Durbin, R., Falquet, L., Fleischman, W., Gouzy, J., Hermjakob, H., Hulo, N., Jonassen, I., Kahn, D., Kanapin, A., ... Zdobnov, E. M. (2000). InterPro-an integrated documentation resource for protein families, domains and functional sites. Bioinformatics, 16(12), 1145-1150. https://doi.org/10.1093/bioinformatics/16.12.1145

@article{dc4971b0b10748a4b9e06dd4f028e402,

title = "InterPro-an integrated documentation resource for protein families, domains and functional sites",

abstract = "Motivation: InterPro is a new integrated documentation resource for protein families, domains and functional sites, developed initially as a means of rationalising the complementary efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Results: Merged annotations from PRINTS, PROSITE and Pfam form the InterPro core. Each combined InterPro entry includes functional descriptions and literature references, and links are made back to the relevant parent database(s), allowing users to see at a glance whether a particular family or domain has associated patterns, profiles, fingerprints, etc. Merged and individual entries (i.e. those that have no counterpart in the companion resources) are assigned unique accession numbers. Release 1.2 of InterPro (June 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification (PTMs) encoded by 6581 different regular expressions, profiles, fingerprints and Hidden Markov Models (HMMs). Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1 000 000 hits from 264 333 different proteins out of 384 572 in SWISS-PROT and TrEMBL.",

author = "R. Apweiler and Attwood, {T. K.} and A. Bairoch and A. Bateman and E. Birney and M. Biswas and P. Bucher and L. Cerutti and F. Corpet and Croning, {M. D R} and R. Durbin and L. Falquet and W. Fleischman and J. Gouzy and H. Hermjakob and N. Hulo and I. Jonassen and D. Kahn and A. Kanapin and Y. Karavidopoulou and R. Lopez and B. Marx and Mulder, {N. J.} and Oinn, {T. M.} and M. Pagni and F. Servant and Sigrist, {C. J A} and Zdobnov, {E. M.}",

year = "2000",

doi = "10.1093/bioinformatics/16.12.1145",

language = "English",

volume = "16",

pages = "1145--1150",

journal = "Bioinformatics",

issn = "1460-2059",

publisher = "Oxford University Press",

number = "12",

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Apweiler, R, Attwood, TK, Bairoch, A, Bateman, A, Birney, E, Biswas, M, Bucher, P, Cerutti, L, Corpet, F, Croning, MDR, Durbin, R, Falquet, L, Fleischman, W, Gouzy, J, Hermjakob, H, Hulo, N, Jonassen, I, Kahn, D, Kanapin, A, Karavidopoulou, Y, Lopez, R, Marx, B, Mulder, NJ, Oinn, TM, Pagni, M, Servant, F, Sigrist, CJA & Zdobnov, EM 2000, 'InterPro-an integrated documentation resource for protein families, domains and functional sites', Bioinformatics, vol. 16, no. 12, pp. 1145-1150. https://doi.org/10.1093/bioinformatics/16.12.1145

TY - JOUR

T1 - InterPro-an integrated documentation resource for protein families, domains and functional sites

AU - Apweiler, R.

AU - Attwood, T. K.

AU - Bairoch, A.

AU - Bateman, A.

AU - Birney, E.

AU - Biswas, M.

AU - Bucher, P.

AU - Cerutti, L.

AU - Corpet, F.

AU - Croning, M. D R

AU - Durbin, R.

AU - Falquet, L.

AU - Fleischman, W.

AU - Gouzy, J.

AU - Hermjakob, H.

AU - Hulo, N.

AU - Jonassen, I.

AU - Kahn, D.

AU - Kanapin, A.

AU - Karavidopoulou, Y.

AU - Lopez, R.

AU - Marx, B.

AU - Mulder, N. J.

AU - Oinn, T. M.

AU - Pagni, M.

AU - Servant, F.

AU - Sigrist, C. J A

AU - Zdobnov, E. M.

PY - 2000

Y1 - 2000

N2 - Motivation: InterPro is a new integrated documentation resource for protein families, domains and functional sites, developed initially as a means of rationalising the complementary efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Results: Merged annotations from PRINTS, PROSITE and Pfam form the InterPro core. Each combined InterPro entry includes functional descriptions and literature references, and links are made back to the relevant parent database(s), allowing users to see at a glance whether a particular family or domain has associated patterns, profiles, fingerprints, etc. Merged and individual entries (i.e. those that have no counterpart in the companion resources) are assigned unique accession numbers. Release 1.2 of InterPro (June 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification (PTMs) encoded by 6581 different regular expressions, profiles, fingerprints and Hidden Markov Models (HMMs). Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1 000 000 hits from 264 333 different proteins out of 384 572 in SWISS-PROT and TrEMBL.

AB - Motivation: InterPro is a new integrated documentation resource for protein families, domains and functional sites, developed initially as a means of rationalising the complementary efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Results: Merged annotations from PRINTS, PROSITE and Pfam form the InterPro core. Each combined InterPro entry includes functional descriptions and literature references, and links are made back to the relevant parent database(s), allowing users to see at a glance whether a particular family or domain has associated patterns, profiles, fingerprints, etc. Merged and individual entries (i.e. those that have no counterpart in the companion resources) are assigned unique accession numbers. Release 1.2 of InterPro (June 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification (PTMs) encoded by 6581 different regular expressions, profiles, fingerprints and Hidden Markov Models (HMMs). Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1 000 000 hits from 264 333 different proteins out of 384 572 in SWISS-PROT and TrEMBL.

U2 - 10.1093/bioinformatics/16.12.1145

DO - 10.1093/bioinformatics/16.12.1145

M3 - Article

C2 - 11159333

SN - 1460-2059

VL - 16

SP - 1145

EP - 1150

JO - Bioinformatics

JF - Bioinformatics

IS - 12

ER -

InterPro-an integrated documentation resource for protein families, domains and functional sites

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