Intervention for infants at risk of developing Autism: a case series

Jonathan Green, Ming Wai Wan, Jeanne Guiraud, Samina Holsgrove, Janet McNally, Vicky Slonims, Mayada Elsabbagh, Tony Charman, Andrew Pickles, Mark Johnson

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    Theory and evidence suggest the potential value of prodromal intervention for infants at risk of developing autism. We report an initial case series (n = 8) of a parent-mediated, video-aided and interaction-focused intervention with infant siblings of autistic probands, beginning at 8-10 months of age. We outline the theory and evidence base behind this model and present data on feasibility, acceptability and measures ranging from parent-infant social interaction, to infant atypical behaviors, attention and cognition. The intervention proves to be both feasible and acceptable to families. Measurement across domains was successful and on larger samples promise to be an effective test of whether such an intervention in infancy will modify emergent atypical developmental trajectories in infants at risk for autism. © 2013 Springer Science+Business Media New York.
    Original languageEnglish
    Pages (from-to)2502-2514
    Number of pages12
    JournalJournal of Autism and Developmental Disorders
    Issue number11
    Publication statusPublished - 2013


    • Autism
    • Infancy
    • Intervention
    • Parent-child interaction
    • Prodromal


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