Intraosseous thrombosis in ischemic necrosis of bone and osteoarthritis

P. A. Cheras, A. J. Freemont, J. M. Sikorski

    Research output: Contribution to journalArticlepeer-review


    It has been proposed that nontraumatic ischemic necrosis of bone (INB) is a result of lipid associated intraosseous thrombosis. A histological study of 15 patients with INB confirmed the presence of intravascular lipid and thrombosis in the vessels of the femoral head. A similar analysis of 11 patients with primary osteoarthritis (OA) showed similar changes at lower levels. These changes were not observed in seven control femoral heads. The possibility that both INB and OA result from intraosseous thrombosis is discussed. © 1993 Osteoarthritis Research Society.
    Original languageEnglish
    Pages (from-to)219-232
    Number of pages13
    JournalOsteoarthritis and Cartilage
    Issue number4
    Publication statusPublished - Oct 1993


    • Ischemic necrosis of bone
    • lipid
    • Osteoarthritis
    • thrombosis


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