Introduction to metabolomics and its applications in ophthalmology

S Z Tan; P Begley; G Mullard; K A Hollywood; P N Bishop

doi:10.1038/eye.2016.37

Introduction to metabolomics and its applications in ophthalmology

S Z Tan, P Begley, G Mullard, K A Hollywood, P N Bishop

Research output: Contribution to journal › Article › peer-review

Abstract

Metabolomics is the study of endogenous and exogenous metabolites in biological systems, which aims to provide comparative semi-quantitative information about all metabolites in the system. Metabolomics is an emerging and potentially powerful tool in ophthalmology research. It is therefore important for health professionals and researchers involved in the speciality to understand the basic principles of metabolomics experiments. This article provides an overview of the experimental workflow and examples of its use in ophthalmology research from the study of disease metabolism and pathogenesis to identification of biomarkers.

Original language	English
Pages (from-to)	773-783
Number of pages	11
Journal	Eye (London, England)
Volume	30
Issue number	6
Early online date	18 Mar 2016
DOIs	https://doi.org/10.1038/eye.2016.37
Publication status	Published - Jun 2016

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10.1038/eye.2016.37

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abstract = "Metabolomics is the study of endogenous and exogenous metabolites in biological systems, which aims to provide comparative semi-quantitative information about all metabolites in the system. Metabolomics is an emerging and potentially powerful tool in ophthalmology research. It is therefore important for health professionals and researchers involved in the speciality to understand the basic principles of metabolomics experiments. This article provides an overview of the experimental workflow and examples of its use in ophthalmology research from the study of disease metabolism and pathogenesis to identification of biomarkers.",

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AB - Metabolomics is the study of endogenous and exogenous metabolites in biological systems, which aims to provide comparative semi-quantitative information about all metabolites in the system. Metabolomics is an emerging and potentially powerful tool in ophthalmology research. It is therefore important for health professionals and researchers involved in the speciality to understand the basic principles of metabolomics experiments. This article provides an overview of the experimental workflow and examples of its use in ophthalmology research from the study of disease metabolism and pathogenesis to identification of biomarkers.

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Introduction to metabolomics and its applications in ophthalmology

Abstract

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