Introduction to vectors for suicide gene therapy.

CJ Springer

Introduction to vectors for suicide gene therapy.

CJ Springer

Cancer Research UK Manchester Institute

Research output: Contribution to journal › Article › peer-review

Abstract

Suicide gene therapy requires vectors or vehicles capable of efficient and selective gene delivery of the therapeutic genes to tumor cells. A number of vector systems has been proposed for gene therapy. These include: the viral vectors, adenoviruses, (adeno-associated viruses (AAV), herpes simplex virus (1), parvoviruses, lentiviruses, retroviruses (2,3), naked DNA (with or without electroporation) (4), bacteria —and nonviral vectors—cationic lipids, liposomes, polyethyleneimine (PEI), polyamino acids, peptides, and dendrimers.

Original language	English
Pages (from-to)	29-45
Number of pages	17
Journal	Methods in Molecular Medicine
Volume	90
Publication status	Published - 2004

Keywords

Transfection Efficiency
Cytosine Deaminase
Thymidine Kinase Gene
Nonviral Vector
Vascular Endothelial Growth Factor Promoter

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Introduction to vectors for suicide gene therapy.",

abstract = "Suicide gene therapy requires vectors or vehicles capable of efficient and selective gene delivery of the therapeutic genes to tumor cells. A number of vector systems has been proposed for gene therapy. These include: the viral vectors, adenoviruses, (adeno-associated viruses (AAV), herpes simplex virus (1), parvoviruses, lentiviruses, retroviruses (2,3), naked DNA (with or without electroporation) (4), bacteria —and nonviral vectors—cationic lipids, liposomes, polyethyleneimine (PEI), polyamino acids, peptides, and dendrimers.",

keywords = "Transfection Efficiency, Cytosine Deaminase, Thymidine Kinase Gene, Nonviral Vector, Vascular Endothelial Growth Factor Promoter",

author = "CJ Springer",

year = "2004",

language = "English",

volume = "90",

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journal = "Methods in Molecular Medicine",

issn = "1543-1894",

publisher = "Humana Press, Inc",

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AB - Suicide gene therapy requires vectors or vehicles capable of efficient and selective gene delivery of the therapeutic genes to tumor cells. A number of vector systems has been proposed for gene therapy. These include: the viral vectors, adenoviruses, (adeno-associated viruses (AAV), herpes simplex virus (1), parvoviruses, lentiviruses, retroviruses (2,3), naked DNA (with or without electroporation) (4), bacteria —and nonviral vectors—cationic lipids, liposomes, polyethyleneimine (PEI), polyamino acids, peptides, and dendrimers.

KW - Transfection Efficiency

KW - Cytosine Deaminase

KW - Thymidine Kinase Gene

KW - Nonviral Vector

KW - Vascular Endothelial Growth Factor Promoter

UR - http://europepmc.org/abstract/med/14657557

M3 - Article

C2 - 14657557

SN - 1543-1894

VL - 90

SP - 29

EP - 45

JO - Methods in Molecular Medicine

JF - Methods in Molecular Medicine

ER -

Introduction to vectors for suicide gene therapy.

Abstract

Keywords

UN SDGs

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