Ischemia in broca area is associated with broca aphasia more reliably in acute than in chronic stroke

Elisa Ochfeld; Melissa Newhart; John Molitoris; Richard Leigh; Lauren Cloutman; Cameron Davis; Jennifer Crinion; Argye E. Hillis

doi:10.1161/STROKEAHA.109.570374

Ischemia in broca area is associated with broca aphasia more reliably in acute than in chronic stroke

Elisa Ochfeld, Melissa Newhart, John Molitoris, Richard Leigh, Lauren Cloutman, Cameron Davis, Jennifer Crinion, Argye E. Hillis

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Abstract

Background and Purpose-We aimed to determine if ischemia involving Broca area predicts Broca aphasia more reliably in acute or chronic stroke. Methods-We included consecutive right-hand-dominant patients with left hemisphere ischemic stroke (6 months after stroke for chronic stroke). MRI scans were analyzed for ischemic lesions or hypoperfusion in Broca area (Brodmann areas 44 and 45). Patients were scored on the Western Aphasia Battery to classify aphasia syndromes; χ tests were used to identify significant associations. Results-The presence of infarct involving any part of Broca area and the presence of Broca or global aphasia was much stronger in acute (χ=38.1; df1; P

Original language	English
Pages (from-to)	325-330
Number of pages	5
Journal	Stroke
Volume	41
Issue number	2
DOIs	https://doi.org/10.1161/STROKEAHA.109.570374
Publication status	Published - Feb 2010

Keywords

Acute stroke
Aphasia
Brain imaging
Cognitive impairment
Ischemia
Magnetic resonance

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10.1161/STROKEAHA.109.570374

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title = "Ischemia in broca area is associated with broca aphasia more reliably in acute than in chronic stroke",

abstract = "Background and Purpose-We aimed to determine if ischemia involving Broca area predicts Broca aphasia more reliably in acute or chronic stroke. Methods-We included consecutive right-hand-dominant patients with left hemisphere ischemic stroke (6 months after stroke for chronic stroke). MRI scans were analyzed for ischemic lesions or hypoperfusion in Broca area (Brodmann areas 44 and 45). Patients were scored on the Western Aphasia Battery to classify aphasia syndromes; χ tests were used to identify significant associations. Results-The presence of infarct involving any part of Broca area and the presence of Broca or global aphasia was much stronger in acute (χ=38.1; df1; P",

keywords = "Acute stroke, Aphasia, Brain imaging, Cognitive impairment, Ischemia, Magnetic resonance",

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T1 - Ischemia in broca area is associated with broca aphasia more reliably in acute than in chronic stroke

AU - Ochfeld, Elisa

AU - Newhart, Melissa

AU - Molitoris, John

AU - Leigh, Richard

AU - Cloutman, Lauren

AU - Davis, Cameron

AU - Crinion, Jennifer

AU - Hillis, Argye E.

PY - 2010/2

Y1 - 2010/2

N2 - Background and Purpose-We aimed to determine if ischemia involving Broca area predicts Broca aphasia more reliably in acute or chronic stroke. Methods-We included consecutive right-hand-dominant patients with left hemisphere ischemic stroke (6 months after stroke for chronic stroke). MRI scans were analyzed for ischemic lesions or hypoperfusion in Broca area (Brodmann areas 44 and 45). Patients were scored on the Western Aphasia Battery to classify aphasia syndromes; χ tests were used to identify significant associations. Results-The presence of infarct involving any part of Broca area and the presence of Broca or global aphasia was much stronger in acute (χ=38.1; df1; P

AB - Background and Purpose-We aimed to determine if ischemia involving Broca area predicts Broca aphasia more reliably in acute or chronic stroke. Methods-We included consecutive right-hand-dominant patients with left hemisphere ischemic stroke (6 months after stroke for chronic stroke). MRI scans were analyzed for ischemic lesions or hypoperfusion in Broca area (Brodmann areas 44 and 45). Patients were scored on the Western Aphasia Battery to classify aphasia syndromes; χ tests were used to identify significant associations. Results-The presence of infarct involving any part of Broca area and the presence of Broca or global aphasia was much stronger in acute (χ=38.1; df1; P

KW - Acute stroke

KW - Aphasia

KW - Brain imaging

KW - Cognitive impairment

KW - Ischemia

KW - Magnetic resonance

U2 - 10.1161/STROKEAHA.109.570374

DO - 10.1161/STROKEAHA.109.570374

M3 - Article

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VL - 41

SP - 325

EP - 330

JO - Stroke

JF - Stroke

IS - 2

ER -

Ischemia in broca area is associated with broca aphasia more reliably in acute than in chronic stroke

Abstract

Keywords

UN SDGs

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