Isotope specific resolution modelling image reconstruction for high resolution PET imaging

Fotis A. Kotasidis; Jose M. Anton-Rodriguez; Georgios I. Angelis; Julian C. Matthews; Andrew J. Reader; Habib Zaidi

doi:10.1109/NSSMIC.2013.6829235

Isotope specific resolution modelling image reconstruction for high resolution PET imaging

Fotis A. Kotasidis, Jose M. Anton-Rodriguez, Georgios I. Angelis, Julian C. Matthews, Andrew J. Reader, Habib Zaidi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Measuring the spatially variant point spread function (PSF) on a PET scanner involves using a point source to sample the field of view (FOV) at multiple locations. However, since most clinically used isotopes have short half-lives, usually other non-clinically used long-lived isotopes are employed in practice. As such, due to the difference in positron range, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed, are used within resolution modelling (RM) image reconstruction, usually underestimating the true PSF. In our previous work, the spatially variant PSF was measured on the HRRT based on clinically used isotopes. Here we extend the work by evaluating the impact of using isotope-specific PSF maps within RM image reconstruction. Evaluation is performed using point source, phantom and clinical datasets. Results suggest that further improvements in spatial resolution and contrast can be obtained by using an isotope-specific PSF. © 2013 IEEE.

Original language	English
Title of host publication	IEEE Nuclear Science Symposium Conference Record\|IEEE Nucl. Sci. Symp. Conf. Rec.
Publisher	IEEE
ISBN (Print)	9781479905348
DOIs	https://doi.org/10.1109/NSSMIC.2013.6829235
Publication status	Published - 2013
Event	2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013 - Seoul Duration: 1 Jul 2013 → … http://www.nss-mic.org/2013/program/ListProgramDB.asp?session=M18#39

Conference

Conference	2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013
City	Seoul
Period	1/07/13 → …
Internet address	http://www.nss-mic.org/2013/program/ListProgramDB.asp?session=M18#39

Keywords

HRRT
positron range
PSF reconstruction

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10.1109/NSSMIC.2013.6829235

Cite this

@inproceedings{7668f1ff62a6483faf2b881eafbc51c5,

title = "Isotope specific resolution modelling image reconstruction for high resolution PET imaging",

abstract = "Measuring the spatially variant point spread function (PSF) on a PET scanner involves using a point source to sample the field of view (FOV) at multiple locations. However, since most clinically used isotopes have short half-lives, usually other non-clinically used long-lived isotopes are employed in practice. As such, due to the difference in positron range, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed, are used within resolution modelling (RM) image reconstruction, usually underestimating the true PSF. In our previous work, the spatially variant PSF was measured on the HRRT based on clinically used isotopes. Here we extend the work by evaluating the impact of using isotope-specific PSF maps within RM image reconstruction. Evaluation is performed using point source, phantom and clinical datasets. Results suggest that further improvements in spatial resolution and contrast can be obtained by using an isotope-specific PSF. {\textcopyright} 2013 IEEE.",

keywords = "HRRT, positron range, PSF reconstruction",

author = "Kotasidis, {Fotis A.} and Anton-Rodriguez, {Jose M.} and Angelis, {Georgios I.} and Matthews, {Julian C.} and Reader, {Andrew J.} and Habib Zaidi",

year = "2013",

doi = "10.1109/NSSMIC.2013.6829235",

language = "English",

isbn = "9781479905348",

booktitle = "IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec.",

publisher = "IEEE",

address = "United States",

note = "2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013 ; Conference date: 01-07-2013",

url = "http://www.nss-mic.org/2013/program/ListProgramDB.asp?session=M18#39",

}

Kotasidis, FA, Anton-Rodriguez, JM, Angelis, GI, Matthews, JC, Reader, AJ & Zaidi, H 2013, Isotope specific resolution modelling image reconstruction for high resolution PET imaging. in IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec.. IEEE, 2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013, Seoul, 1/07/13. https://doi.org/10.1109/NSSMIC.2013.6829235

TY - GEN

T1 - Isotope specific resolution modelling image reconstruction for high resolution PET imaging

AU - Kotasidis, Fotis A.

AU - Anton-Rodriguez, Jose M.

AU - Angelis, Georgios I.

AU - Matthews, Julian C.

AU - Reader, Andrew J.

AU - Zaidi, Habib

PY - 2013

Y1 - 2013

N2 - Measuring the spatially variant point spread function (PSF) on a PET scanner involves using a point source to sample the field of view (FOV) at multiple locations. However, since most clinically used isotopes have short half-lives, usually other non-clinically used long-lived isotopes are employed in practice. As such, due to the difference in positron range, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed, are used within resolution modelling (RM) image reconstruction, usually underestimating the true PSF. In our previous work, the spatially variant PSF was measured on the HRRT based on clinically used isotopes. Here we extend the work by evaluating the impact of using isotope-specific PSF maps within RM image reconstruction. Evaluation is performed using point source, phantom and clinical datasets. Results suggest that further improvements in spatial resolution and contrast can be obtained by using an isotope-specific PSF. © 2013 IEEE.

AB - Measuring the spatially variant point spread function (PSF) on a PET scanner involves using a point source to sample the field of view (FOV) at multiple locations. However, since most clinically used isotopes have short half-lives, usually other non-clinically used long-lived isotopes are employed in practice. As such, due to the difference in positron range, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed, are used within resolution modelling (RM) image reconstruction, usually underestimating the true PSF. In our previous work, the spatially variant PSF was measured on the HRRT based on clinically used isotopes. Here we extend the work by evaluating the impact of using isotope-specific PSF maps within RM image reconstruction. Evaluation is performed using point source, phantom and clinical datasets. Results suggest that further improvements in spatial resolution and contrast can be obtained by using an isotope-specific PSF. © 2013 IEEE.

KW - HRRT

KW - positron range

KW - PSF reconstruction

U2 - 10.1109/NSSMIC.2013.6829235

DO - 10.1109/NSSMIC.2013.6829235

M3 - Conference contribution

SN - 9781479905348

BT - IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec.

PB - IEEE

T2 - 2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013

Y2 - 1 July 2013

ER -

Isotope specific resolution modelling image reconstruction for high resolution PET imaging

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Keywords

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