Abstract
Studies have established the magnitude of the genetic basis of juvenile idiopathic arthritis (JIA). JIA is a complex genetic condition and the genes that influence susceptibility are actively being sought. A candidate gene approach is being used by several groups. MHC-, cytokine- and T-cell-related genes have all been positively associated with JIA. Here we review some of the latest genetic data, and discuss ways in which JIA genetic research might proceed
Original language | English |
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Journal | Arthritis Res |
Volume | 4, 5 |
Publication status | Published - 2002 |
Keywords
- Arthritis
- Arthritis,Juvenile Rheumatoid
- Child
- Child,Preschool
- epidemiology
- Epidemiology,Molecular
- Gene Expression Profiling
- Genetic Predisposition to Disease
- genetics
- Genotype
- Human
- immunology
- International Cooperation
- Research
- World Health