Keloid disease: Clinical relevance of single versus multiple site scars

Duncan Mcgrouther, Ardeshir Bayat, G. Arscott, W. E R Ollier, D. A. Mc Grouther, M. W J Ferguson

    Research output: Contribution to journalArticlepeer-review


    Much of our current understanding of keloid disease (KD) is based on anecdote rather than objective observation and statistical analysis. To elucidate further the aetiology of KD, we compared the profiles of patients with single versus multiple anatomical site keloid scars. We studied the clinical characteristics of 211 cases of keloid scarring, 137 (65%) females and 74 (35%) males. There were 122 cases with scars in single anatomical site and 89 cases with 369 scars in multiple anatomical sites entered into the study. Patients were of Afrocaribbean origin that presented to the department of Plastic and Reconstructive Surgery at the University of West Indies in Kingston, Jamaica. A total number of 491 keloid scars (single and multiple sites) were evaluated in the study. Data were collected on multiple parameters. The association of age of onset, anatomical area, cause of scarring, sex of the patient, presence or absence of family and medical history in patients with single as opposed to multiple site keloid scars were examined in detail and statistically evaluated. The formation of keloid scars in multiple anatomical sites was found to be statistically significant in that it was more common in younger age groups (p0.05). More than 50% (111) of all keloid cases had a positive family history of keloid scarring, and family history was strongly associated with the formation of keloid scars in multiple sites as opposed to a single anatomical site (p
    Original languageEnglish
    Pages (from-to)28-37
    Number of pages9
    JournalBritish Journal of Plastic Surgery
    Issue number1
    Publication statusPublished - Jan 2005


    • Anatomical site-specific scars
    • Family history
    • Heterogeneity
    • Keloid disease
    • Multiple site scars
    • Single site scars
    • Skin scarring


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