Lateral asymmetry in the shape of brain ventricles in control and schizophrenia groups

J. Graham; K. O. Babalola; W. G. Honer; D. Lang; L. Kopala; R. Vandorpe

doi:10.1109/ISBI.2006.1624941

Lateral asymmetry in the shape of brain ventricles in control and schizophrenia groups

J. Graham, K. O. Babalola, W. G. Honer, D. Lang, L. Kopala, R. Vandorpe

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Abstract

We use point distribution models (PDMs) to investigate lateral asymmetries in the shape of brain ventricles between control subjects and people with schizophrenia. Ventricle surfaces were extracted from T2-weighted MR images and PDMs generated using structural correspondences on the individual surfaces. Using paired linear discriminant analysis we calculate the vector in shape space that maximally separates the shapes of right and left ventricles in the group. The magnitude of the asymmetry is quantified by projection of the individual ventricle shapes onto this vector. We observe significant differences in the magnitude of the asymmetry in both schizophrenia and control groups. There is also a clear difference in the pattern of asymmetry. Male and female subgroups show different magnitudes and patterns of asymmetry, in both groups. © 2006 IEEE.

Original language	English
Title of host publication	2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings\|IEEE Int. Symp. Biomed. Imag. Nano Macro Proc.
Publisher	IEEE
Pages	414-417
Number of pages	3
Volume	2006
ISBN (Print)	0780395778, 9780780395770
DOIs	https://doi.org/10.1109/ISBI.2006.1624941
Publication status	Published - 2006
Event	2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Arlington, VA Duration: 1 Jul 2006 → …

Conference

Conference	2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro
City	Arlington, VA
Period	1/07/06 → …

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Graham, J., Babalola, K. O., Honer, W. G., Lang, D., Kopala, L., & Vandorpe, R. (2006). Lateral asymmetry in the shape of brain ventricles in control and schizophrenia groups. In 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings|IEEE Int. Symp. Biomed. Imag. Nano Macro Proc. (Vol. 2006, pp. 414-417). IEEE. https://doi.org/10.1109/ISBI.2006.1624941

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abstract = "We use point distribution models (PDMs) to investigate lateral asymmetries in the shape of brain ventricles between control subjects and people with schizophrenia. Ventricle surfaces were extracted from T2-weighted MR images and PDMs generated using structural correspondences on the individual surfaces. Using paired linear discriminant analysis we calculate the vector in shape space that maximally separates the shapes of right and left ventricles in the group. The magnitude of the asymmetry is quantified by projection of the individual ventricle shapes onto this vector. We observe significant differences in the magnitude of the asymmetry in both schizophrenia and control groups. There is also a clear difference in the pattern of asymmetry. Male and female subgroups show different magnitudes and patterns of asymmetry, in both groups. {\textcopyright} 2006 IEEE.",

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Graham, J, Babalola, KO, Honer, WG, Lang, D, Kopala, L & Vandorpe, R 2006, Lateral asymmetry in the shape of brain ventricles in control and schizophrenia groups. in 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings|IEEE Int. Symp. Biomed. Imag. Nano Macro Proc.. vol. 2006, IEEE, pp. 414-417, 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Arlington, VA, 1/07/06. https://doi.org/10.1109/ISBI.2006.1624941

Lateral asymmetry in the shape of brain ventricles in control and schizophrenia groups. / Graham, J.; Babalola, K. O.; Honer, W. G. et al.
2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings|IEEE Int. Symp. Biomed. Imag. Nano Macro Proc.. Vol. 2006 IEEE, 2006. p. 414-417.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Lateral asymmetry in the shape of brain ventricles in control and schizophrenia groups

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