Lexical decision of nonwords and pseudowords in humans: A positron emission tomography study

Karsten Specht; Chrisitane Holtel; Roland Zahn; Hans Herzog; Bernd J. Krause; Felix M. Mottaghy; Irmgard Radermacher; Daniela Schmidt; Lutz Tellmann; Susanne Weis; Klaus Willmes; Walter Huber

doi:10.1016/S0304-3940(03)00494-4

Lexical decision of nonwords and pseudowords in humans: A positron emission tomography study

Karsten Specht, Chrisitane Holtel, Roland Zahn, Hans Herzog, Bernd J. Krause, Felix M. Mottaghy, Irmgard Radermacher, Daniela Schmidt, Lutz Tellmann, Susanne Weis, Klaus Willmes, Walter Huber

Research output: Contribution to journal › Article › peer-review

Abstract

In this functional positron emission tomography study brain activations during an auditory lexical decision task with two experimental conditions were investigated. First, the subjects had to discriminate between real words and nonwords; second, real words varied with pseudowords. Comparing each of these tasks to an auditory control condition we found bilateral activation of the superior temporal and inferior frontal gyrus, lateralized to the left in the pseudoword condition. The comparison of the lexical decision tasks revealed higher rCBF during the pseudo-/real word decisions within BA 47, adjacent to Broca's area, and the anterior cingulate. The data support the notion that the lexical decision during a nonword task is mainly based on a phonological discrimination process, whereas a pseudoword task more strongly requires lexical access resulting in activation of BA 47. © 2003 Elsevier Science Ireland Ltd. All rights reserved.

Original language	English
Pages (from-to)	177-181
Number of pages	4
Journal	Neuroscience letters
Volume	345
Issue number	3
DOIs	https://doi.org/10.1016/S0304-3940(03)00494-4
Publication status	Published - 24 Jul 2003

Keywords

Brain mapping
Hemispheric dominance
Language
Lateralization
Lexical decision
Positron emission tomography
Semantics

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10.1016/S0304-3940(03)00494-4

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title = "Lexical decision of nonwords and pseudowords in humans: A positron emission tomography study",

abstract = "In this functional positron emission tomography study brain activations during an auditory lexical decision task with two experimental conditions were investigated. First, the subjects had to discriminate between real words and nonwords; second, real words varied with pseudowords. Comparing each of these tasks to an auditory control condition we found bilateral activation of the superior temporal and inferior frontal gyrus, lateralized to the left in the pseudoword condition. The comparison of the lexical decision tasks revealed higher rCBF during the pseudo-/real word decisions within BA 47, adjacent to Broca's area, and the anterior cingulate. The data support the notion that the lexical decision during a nonword task is mainly based on a phonological discrimination process, whereas a pseudoword task more strongly requires lexical access resulting in activation of BA 47. {\textcopyright} 2003 Elsevier Science Ireland Ltd. All rights reserved.",

keywords = "Brain mapping, Hemispheric dominance, Language, Lateralization, Lexical decision, Positron emission tomography, Semantics",

author = "Karsten Specht and Chrisitane Holtel and Roland Zahn and Hans Herzog and Krause, {Bernd J.} and Mottaghy, {Felix M.} and Irmgard Radermacher and Daniela Schmidt and Lutz Tellmann and Susanne Weis and Klaus Willmes and Walter Huber",

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T1 - Lexical decision of nonwords and pseudowords in humans: A positron emission tomography study

AU - Specht, Karsten

AU - Holtel, Chrisitane

AU - Zahn, Roland

AU - Herzog, Hans

AU - Krause, Bernd J.

AU - Mottaghy, Felix M.

AU - Radermacher, Irmgard

AU - Schmidt, Daniela

AU - Tellmann, Lutz

AU - Weis, Susanne

AU - Willmes, Klaus

AU - Huber, Walter

N1 - 0304-3940 (Print)Comparative StudyJournal Article

PY - 2003/7/24

Y1 - 2003/7/24

N2 - In this functional positron emission tomography study brain activations during an auditory lexical decision task with two experimental conditions were investigated. First, the subjects had to discriminate between real words and nonwords; second, real words varied with pseudowords. Comparing each of these tasks to an auditory control condition we found bilateral activation of the superior temporal and inferior frontal gyrus, lateralized to the left in the pseudoword condition. The comparison of the lexical decision tasks revealed higher rCBF during the pseudo-/real word decisions within BA 47, adjacent to Broca's area, and the anterior cingulate. The data support the notion that the lexical decision during a nonword task is mainly based on a phonological discrimination process, whereas a pseudoword task more strongly requires lexical access resulting in activation of BA 47. © 2003 Elsevier Science Ireland Ltd. All rights reserved.

AB - In this functional positron emission tomography study brain activations during an auditory lexical decision task with two experimental conditions were investigated. First, the subjects had to discriminate between real words and nonwords; second, real words varied with pseudowords. Comparing each of these tasks to an auditory control condition we found bilateral activation of the superior temporal and inferior frontal gyrus, lateralized to the left in the pseudoword condition. The comparison of the lexical decision tasks revealed higher rCBF during the pseudo-/real word decisions within BA 47, adjacent to Broca's area, and the anterior cingulate. The data support the notion that the lexical decision during a nonword task is mainly based on a phonological discrimination process, whereas a pseudoword task more strongly requires lexical access resulting in activation of BA 47. © 2003 Elsevier Science Ireland Ltd. All rights reserved.

KW - Brain mapping

KW - Hemispheric dominance

KW - Language

KW - Lateralization

KW - Lexical decision

KW - Positron emission tomography

KW - Semantics

U2 - 10.1016/S0304-3940(03)00494-4

DO - 10.1016/S0304-3940(03)00494-4

M3 - Article

SN - 0304-3940

VL - 345

SP - 177

EP - 181

JO - Neuroscience letters

JF - Neuroscience letters

IS - 3

ER -

Lexical decision of nonwords and pseudowords in humans: A positron emission tomography study

Abstract

Keywords

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