Longitudinal measurements of signal intensity as a potential marker for cartilage degeneration in osteoarthritis

J. H. Naish, G. Vincent, M. Bowes, M. Kothari, D. White, J. C. Waterton, C. J. Taylor

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    In this study we have developed techniques to compare local changes in signal intensity over time in fat suppressed 3D gradient echo MR images of articular cartilage in patients with osteoarthritis. We have applied these techniques to data taken over a periods of 1 and 3 years in two groups of patients with established OA of the knee. In both these studies, no significant change in total cartilage volume could be detected but we were able to observe some significant changes in signal intensity. We conclude that in a study of cartilage structure this technique can provide additional information without the overhead of extra scans. © 2004 IEEE.
    Original languageEnglish
    Title of host publication2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano|IEEE Int. Symp. Biomed. Imaging Macro Nano
    PublisherIEEE
    Pages205-208
    Number of pages3
    Volume1
    ISBN (Print)0780383885
    Publication statusPublished - 2004
    Event2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA
    Duration: 1 Jul 2004 → …
    http://<Go to ISI>://ISIP:000227671300052

    Conference

    Conference2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
    CityArlington, VA
    Period1/07/04 → …
    Internet address

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