Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: A randomized trial

Marije F. Bakker; Johannes W G Jacobs; Paco M J Welsing; Suzanne M M Verstappen; Janneke Tekstra; Evelien Ton; Monique A W Geurts; Jacobine H. van der Werf; Grietje van Albada-Kuipers; Zalima N. Jahangier-de Veen; Maaike J. van der Veen; Catharina M. Verhoef; Floris P J G Lafeber; Johannes W J Bijlsma

doi:10.1059/0003-4819-156-5-201203060-00004

Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: A randomized trial

Marije F. Bakker, Johannes W G Jacobs, Paco M J Welsing, Suzanne M M Verstappen, Janneke Tekstra, Evelien Ton, Monique A W Geurts, Jacobine H. van der Werf, Grietje van Albada-Kuipers, Zalima N. Jahangier-de Veen, Maaike J. van der Veen, Catharina M. Verhoef, Floris P J G Lafeber, Johannes W J Bijlsma

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Treatment strategies for tight control of early rheumatoid arthritis (RA) are highly effective but can be improved. Objective: To investigate whether adding prednisone, 10 mg/d, at the start of a methotrexate (MTX)-based treatment strategy for tight control in early RA increases its effectiveness. Design: A 2-year, prospective, randomized, placebo-controlled, double-blind, multicenter trial (CAMERA-II [Computer Assisted Management in Early Rheumatoid Arthritis trial-II]). (International Standard Randomised Controlled Trial Number: ISRCTN 70365169) Setting: 7 hospitals in the Netherlands. Patients: 236 patients with early RA (duration

Original language	English
Pages (from-to)	329-339
Number of pages	10
Journal	Annals of Internal Medicine
Volume	156
Issue number	5
DOIs	https://doi.org/10.1059/0003-4819-156-5-201203060-00004
Publication status	Published - 6 Mar 2012

Access to Document

10.1059/0003-4819-156-5-201203060-00004

http://www.annals.org/content/156/5/329.full.pdf#page=1&view=FitH

Cite this

Bakker, M. F., Jacobs, J. W. G., Welsing, P. M. J., Verstappen, S. M. M., Tekstra, J., Ton, E., Geurts, M. A. W., van der Werf, J. H., van Albada-Kuipers, G., Jahangier-de Veen, Z. N., van der Veen, M. J., Verhoef, C. M., Lafeber, F. P. J. G., & Bijlsma, J. W. J. (2012). Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: A randomized trial. Annals of Internal Medicine, 156(5), 329-339. https://doi.org/10.1059/0003-4819-156-5-201203060-00004

@article{3a55b7974b30457b93dc35fb588a91a0,

title = "Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: A randomized trial",

abstract = "Background: Treatment strategies for tight control of early rheumatoid arthritis (RA) are highly effective but can be improved. Objective: To investigate whether adding prednisone, 10 mg/d, at the start of a methotrexate (MTX)-based treatment strategy for tight control in early RA increases its effectiveness. Design: A 2-year, prospective, randomized, placebo-controlled, double-blind, multicenter trial (CAMERA-II [Computer Assisted Management in Early Rheumatoid Arthritis trial-II]). (International Standard Randomised Controlled Trial Number: ISRCTN 70365169) Setting: 7 hospitals in the Netherlands. Patients: 236 patients with early RA (duration",

author = "Bakker, {Marije F.} and Jacobs, {Johannes W G} and Welsing, {Paco M J} and Verstappen, {Suzanne M M} and Janneke Tekstra and Evelien Ton and Geurts, {Monique A W} and {van der Werf}, {Jacobine H.} and {van Albada-Kuipers}, Grietje and {Jahangier-de Veen}, {Zalima N.} and {van der Veen}, {Maaike J.} and Verhoef, {Catharina M.} and Lafeber, {Floris P J G} and Bijlsma, {Johannes W J}",

year = "2012",

month = mar,

day = "6",

doi = "10.1059/0003-4819-156-5-201203060-00004",

language = "English",

volume = "156",

pages = "329--339",

journal = "Annals of Internal Medicine",

issn = "1539-3704",

publisher = "American College of Physicians",

number = "5",

}

Bakker, MF, Jacobs, JWG, Welsing, PMJ, Verstappen, SMM, Tekstra, J, Ton, E, Geurts, MAW, van der Werf, JH, van Albada-Kuipers, G, Jahangier-de Veen, ZN, van der Veen, MJ, Verhoef, CM, Lafeber, FPJG & Bijlsma, JWJ 2012, 'Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: A randomized trial', Annals of Internal Medicine, vol. 156, no. 5, pp. 329-339. https://doi.org/10.1059/0003-4819-156-5-201203060-00004

TY - JOUR

T1 - Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: A randomized trial

AU - Bakker, Marije F.

AU - Jacobs, Johannes W G

AU - Welsing, Paco M J

AU - Verstappen, Suzanne M M

AU - Tekstra, Janneke

AU - Ton, Evelien

AU - Geurts, Monique A W

AU - van der Werf, Jacobine H.

AU - van Albada-Kuipers, Grietje

AU - Jahangier-de Veen, Zalima N.

AU - van der Veen, Maaike J.

AU - Verhoef, Catharina M.

AU - Lafeber, Floris P J G

AU - Bijlsma, Johannes W J

PY - 2012/3/6

Y1 - 2012/3/6

N2 - Background: Treatment strategies for tight control of early rheumatoid arthritis (RA) are highly effective but can be improved. Objective: To investigate whether adding prednisone, 10 mg/d, at the start of a methotrexate (MTX)-based treatment strategy for tight control in early RA increases its effectiveness. Design: A 2-year, prospective, randomized, placebo-controlled, double-blind, multicenter trial (CAMERA-II [Computer Assisted Management in Early Rheumatoid Arthritis trial-II]). (International Standard Randomised Controlled Trial Number: ISRCTN 70365169) Setting: 7 hospitals in the Netherlands. Patients: 236 patients with early RA (duration

AB - Background: Treatment strategies for tight control of early rheumatoid arthritis (RA) are highly effective but can be improved. Objective: To investigate whether adding prednisone, 10 mg/d, at the start of a methotrexate (MTX)-based treatment strategy for tight control in early RA increases its effectiveness. Design: A 2-year, prospective, randomized, placebo-controlled, double-blind, multicenter trial (CAMERA-II [Computer Assisted Management in Early Rheumatoid Arthritis trial-II]). (International Standard Randomised Controlled Trial Number: ISRCTN 70365169) Setting: 7 hospitals in the Netherlands. Patients: 236 patients with early RA (duration

U2 - 10.1059/0003-4819-156-5-201203060-00004

DO - 10.1059/0003-4819-156-5-201203060-00004

M3 - Article

C2 - 22393128

SN - 1539-3704

VL - 156

SP - 329

EP - 339

JO - Annals of Internal Medicine

JF - Annals of Internal Medicine

IS - 5

ER -

Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: A randomized trial

Abstract

Access to Document

Fingerprint

Cite this