Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease.

Peter Lange; Bartolome Celli; Alvar Agustí; Gorm Boje Jensen; Miguel Divo; Rosa Faner; Stefano Guerra; Jacob Louis Marott; Fernando D Martinez; Pablo Martinez-Camblor; Paula Meek; Caroline A Owen; Hans Petersen; Victor Pinto-Plata; Peter Schnohr; Akshay Sood; Joan B Soriano; Yohannes Tesfaigzi; Jørgen Vestbo

doi:10.1056/NEJMoa1411532

Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease.

Peter Lange, Bartolome Celli, Alvar Agustí, Gorm Boje Jensen, Miguel Divo, Rosa Faner, Stefano Guerra, Jacob Louis Marott, Fernando D Martinez, Pablo Martinez-Camblor, Paula Meek, Caroline A Owen, Hans Petersen, Victor Pinto-Plata, Peter Schnohr, Akshay Sood, Joan B Soriano, Yohannes Tesfaigzi, Jørgen Vestbo

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is thought to result from an accelerated decline in forced expiratory volume in 1 second (FEV1) over time. Yet it is possible that a normal decline in FEV1 could also lead to COPD in persons whose maximally attained FEV1 is less than population norms. METHODS: We stratified participants in three independent cohorts (the Framingham Offspring Cohort, the Copenhagen City Heart Study, and the Lovelace Smokers Cohort) according to lung function (FEV1 ≥80% or

Original language	English
Journal	The New England Journal of Medicine
Volume	373
Issue number	2
DOIs	https://doi.org/10.1056/NEJMoa1411532
Publication status	Published - 9 Jul 2015

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10.1056/NEJMoa1411532

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Lange, P., Celli, B., Agustí, A., Boje Jensen, G., Divo, M., Faner, R., Guerra, S., Marott, J. L., Martinez, F. D., Martinez-Camblor, P., Meek, P., Owen, C. A., Petersen, H., Pinto-Plata, V., Schnohr, P., Sood, A., Soriano, J. B., Tesfaigzi, Y., & Vestbo, J. (2015). Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease. The New England Journal of Medicine, 373(2). https://doi.org/10.1056/NEJMoa1411532

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title = "Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease.",

abstract = "BACKGROUND: Chronic obstructive pulmonary disease (COPD) is thought to result from an accelerated decline in forced expiratory volume in 1 second (FEV1) over time. Yet it is possible that a normal decline in FEV1 could also lead to COPD in persons whose maximally attained FEV1 is less than population norms. METHODS: We stratified participants in three independent cohorts (the Framingham Offspring Cohort, the Copenhagen City Heart Study, and the Lovelace Smokers Cohort) according to lung function (FEV1 ≥80% or",

author = "Peter Lange and Bartolome Celli and Alvar Agust{\'i} and {Boje Jensen}, Gorm and Miguel Divo and Rosa Faner and Stefano Guerra and Marott, {Jacob Louis} and Martinez, {Fernando D} and Pablo Martinez-Camblor and Paula Meek and Owen, {Caroline A} and Hans Petersen and Victor Pinto-Plata and Peter Schnohr and Akshay Sood and Soriano, {Joan B} and Yohannes Tesfaigzi and J{\o}rgen Vestbo",

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month = jul,

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Lange, P, Celli, B, Agustí, A, Boje Jensen, G, Divo, M, Faner, R, Guerra, S, Marott, JL, Martinez, FD, Martinez-Camblor, P, Meek, P, Owen, CA, Petersen, H, Pinto-Plata, V, Schnohr, P, Sood, A, Soriano, JB, Tesfaigzi, Y & Vestbo, J 2015, 'Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease.', The New England Journal of Medicine, vol. 373, no. 2. https://doi.org/10.1056/NEJMoa1411532

TY - JOUR

T1 - Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease.

AU - Lange, Peter

AU - Celli, Bartolome

AU - Agustí, Alvar

AU - Boje Jensen, Gorm

AU - Divo, Miguel

AU - Faner, Rosa

AU - Guerra, Stefano

AU - Marott, Jacob Louis

AU - Martinez, Fernando D

AU - Martinez-Camblor, Pablo

AU - Meek, Paula

AU - Owen, Caroline A

AU - Petersen, Hans

AU - Pinto-Plata, Victor

AU - Schnohr, Peter

AU - Sood, Akshay

AU - Soriano, Joan B

AU - Tesfaigzi, Yohannes

AU - Vestbo, Jørgen

N1 - K23 HL094531, NHLBI NIH HHS, United StatesP50HL107165, NHLBI NIH HHS, United StatesR01 ES015482, NIEHS NIH HHS, United StatesR01 HL068111, NHLBI NIH HHS, United States

PY - 2015/7/9

Y1 - 2015/7/9

N2 - BACKGROUND: Chronic obstructive pulmonary disease (COPD) is thought to result from an accelerated decline in forced expiratory volume in 1 second (FEV1) over time. Yet it is possible that a normal decline in FEV1 could also lead to COPD in persons whose maximally attained FEV1 is less than population norms. METHODS: We stratified participants in three independent cohorts (the Framingham Offspring Cohort, the Copenhagen City Heart Study, and the Lovelace Smokers Cohort) according to lung function (FEV1 ≥80% or

AB - BACKGROUND: Chronic obstructive pulmonary disease (COPD) is thought to result from an accelerated decline in forced expiratory volume in 1 second (FEV1) over time. Yet it is possible that a normal decline in FEV1 could also lead to COPD in persons whose maximally attained FEV1 is less than population norms. METHODS: We stratified participants in three independent cohorts (the Framingham Offspring Cohort, the Copenhagen City Heart Study, and the Lovelace Smokers Cohort) according to lung function (FEV1 ≥80% or

U2 - 10.1056/NEJMoa1411532

DO - 10.1056/NEJMoa1411532

M3 - Article

C2 - 26154786

SN - 1533-4406

VL - 373

JO - The New England Journal of Medicine

JF - The New England Journal of Medicine

IS - 2

ER -

Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease.

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