Lymphocyte Subpopulations in Peripheral Blood of Lambs Experimentally Infected with Bovine Respiratory Syncytial Virus

R. Sharma, Z. Woldehiwet, D. G. Spiller, H. M. Warenius

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The lymphocyte subpopulations of peripheral blood of normal lambs and lambs experimentally infected with bovine respiratory syncytial virus (RSV) were analysed by flow cytometry, using a panel of monoclonal antibodies against specific lymphocyte epitopes. Experimental infection with bovine RSV was characterized by a significant rise in SBU-T8+ (CD8+ or cytotoxic) T cells and a significant reduction in SBU-T4+ (CD4+ or helper) T cells and B (LCA p220+) lymphocytes (P
    Original languageEnglish
    Pages (from-to)383-391
    Number of pages8
    JournalVeterinary Immunology and Immunopathology
    Volume24
    Issue number4
    Publication statusPublished - Apr 1990

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