Major histocompatibility complex typing of dogs from Russia shows further dog leukocyte antigen diversity

L. J. Kennedy, J. J. Brown, A. Barnes, W. E R Ollier, S. Knyazev

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Blood samples from 85 Russian dogs and wolves were collected as dried blood spots on paper and transported to the UK by mail. We obtained partial or complete three-locus canine major histocompatibility complex [dog leukocyte antigen (DLA)] class II haplotypes on 81 of these samples. Six new alleles were identified: three DLA-DRB1 and three DLA-DQB1. These alleles occurred in haplotypic combinations not previously seen in other European dogs. One haplotype appeared to lack a DQB1 allele. Two of the new haplotypes segregated through a family of dogs that was investigated. © 2007 The Authors.
    Original languageEnglish
    Pages (from-to)151-156
    Number of pages5
    JournalTissue Antigens
    Volume71
    Issue number2
    DOIs
    Publication statusPublished - Feb 2008

    Keywords

    • Dog leukocyte antigen
    • Major histocompatibility complex
    • Russian dog breeds

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