Making carbon nanotubes biocompatible and biodegradable

Alberto Bianco, Kostas Kostarelos, Maurizio Prato

    Research output: Contribution to journalArticlepeer-review


    Carbon nanotubes are promising nanomaterials with great potential in the field of nanomedicine for both therapeutic and diagnostic applications. Different approaches have been developed to render this material biocompatible and to modulate any ensuing toxic effects. In the context of medical use, although chemically functionalised carbon nanotubes display reduced toxicity, they are still considered with scepticism due to their perceived non-biodegradability. Recently, it has been demonstrated that functionalised carbon nanotubes can be degraded by oxidative enzymes. This finding is offering a new perspective for the development of carbon nanotubes in medicine. This article highlights recent advances that can act as paradigm-shifts towards the design of biocompatible and biodegradable functionalised carbon nanotubes and allow their translation into the clinic. © 2011 The Royal Society of Chemistry.
    Original languageEnglish
    Pages (from-to)10182-10188
    Number of pages6
    JournalChemical Communications
    Issue number37
    Publication statusPublished - 7 Oct 2011


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