Management of a new isolated metastasis during sunitinib treatment in renal cell carcinoma patients: A lesson from two cases

Alaaeldin Shablak; Jackie O'Dwyer; Robert Hawkins; Ruth Board

doi:10.1159/000321908

Management of a new isolated metastasis during sunitinib treatment in renal cell carcinoma patients: A lesson from two cases

Alaaeldin Shablak, Jackie O'Dwyer, Robert Hawkins, Ruth Board

Research output: Contribution to journal › Article › peer-review

Abstract

Metastatic renal cell carcinoma (mRCC) is a difficult to treat malignancy and currently Sunitinib is a standard of care first-line therapy. A new metastasis during the treatment is considered a sign of drug failure and alternative therapeutic methods should be tried. Here, we report 2 cases of newly diagnosed isolated metastasis during Sunitinib treatment of mRCC patients. Our management plan included local palliative therapy to the lesion followed by recommencing of Sunitinib. This resulted in a good symptomatic relief locally as well as good overall control of the disease. Copyright © 2010 S. Karger AG, Basel.

Original language	English
Pages (from-to)	245-248
Number of pages	3
Journal	Urologia Internationalis
Volume	86
Issue number	2
DOIs	https://doi.org/10.1159/000321908
Publication status	Published - Mar 2011

Keywords

Radiotherapy
Renal cell carcinoma
Sunitinib

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1159/000321908

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title = "Management of a new isolated metastasis during sunitinib treatment in renal cell carcinoma patients: A lesson from two cases",

abstract = "Metastatic renal cell carcinoma (mRCC) is a difficult to treat malignancy and currently Sunitinib is a standard of care first-line therapy. A new metastasis during the treatment is considered a sign of drug failure and alternative therapeutic methods should be tried. Here, we report 2 cases of newly diagnosed isolated metastasis during Sunitinib treatment of mRCC patients. Our management plan included local palliative therapy to the lesion followed by recommencing of Sunitinib. This resulted in a good symptomatic relief locally as well as good overall control of the disease. Copyright {\textcopyright} 2010 S. Karger AG, Basel.",

keywords = "Radiotherapy, Renal cell carcinoma, Sunitinib",

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T1 - Management of a new isolated metastasis during sunitinib treatment in renal cell carcinoma patients: A lesson from two cases

AU - Shablak, Alaaeldin

AU - O'Dwyer, Jackie

AU - Hawkins, Robert

AU - Board, Ruth

PY - 2011/3

Y1 - 2011/3

N2 - Metastatic renal cell carcinoma (mRCC) is a difficult to treat malignancy and currently Sunitinib is a standard of care first-line therapy. A new metastasis during the treatment is considered a sign of drug failure and alternative therapeutic methods should be tried. Here, we report 2 cases of newly diagnosed isolated metastasis during Sunitinib treatment of mRCC patients. Our management plan included local palliative therapy to the lesion followed by recommencing of Sunitinib. This resulted in a good symptomatic relief locally as well as good overall control of the disease. Copyright © 2010 S. Karger AG, Basel.

AB - Metastatic renal cell carcinoma (mRCC) is a difficult to treat malignancy and currently Sunitinib is a standard of care first-line therapy. A new metastasis during the treatment is considered a sign of drug failure and alternative therapeutic methods should be tried. Here, we report 2 cases of newly diagnosed isolated metastasis during Sunitinib treatment of mRCC patients. Our management plan included local palliative therapy to the lesion followed by recommencing of Sunitinib. This resulted in a good symptomatic relief locally as well as good overall control of the disease. Copyright © 2010 S. Karger AG, Basel.

KW - Radiotherapy

KW - Renal cell carcinoma

KW - Sunitinib

U2 - 10.1159/000321908

DO - 10.1159/000321908

M3 - Article

SN - 0042-1138

VL - 86

SP - 245

EP - 248

JO - Urologia Internationalis

JF - Urologia Internationalis

IS - 2

ER -

Management of a new isolated metastasis during sunitinib treatment in renal cell carcinoma patients: A lesson from two cases

Abstract

Keywords

UN SDGs

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