Management of suspected viral encephalitis in adults - Association of British Neurologists and British Infection Association National Guidelines

Paul Klapper, T. Solomon, B. D. Michael, P. E. Smith, F. Sanderson, N. W S Davies, I. J. Hart, M. Holland, A. Easton, C. Buckley, R. Kneen, N. J. Beeching

    Research output: Contribution to journalArticlepeer-review

    Abstract

    In the 1980s the outcome of patients with herpes simplex encephalitis was shown to be dramatically improved with aciclovir treatment. Delays in starting treatment, particularly beyond 48 h after hospital admission, are associated with a worse prognosis. Several comprehensive reviews of the investigation and management of encephalitis have been published. However, their impact on day-to day clinical practice appears to be limited. The emergency management of meningitis in children and adults was revolutionised by the introduction of a simple algorithm as part of management guidelines.In February 2008 a group of clinicians met in Liverpool to begin the development process for clinical care guidelines based around a similar simple algorithm, supported by an evidence base, whose implementation is hoped would improve the management of patients with suspected encephalitis. © 2012.
    Original languageEnglish
    Pages (from-to)347-373
    Number of pages26
    JournalJournal Of Infection
    Volume64
    Issue number4
    DOIs
    Publication statusPublished - Apr 2012

    Keywords

    • Antibody-associated encephalitis
    • Encephalitis
    • Enterovirus
    • Herpes simplex virus
    • Immunocompromised
    • Varicella zoster virus
    • Viral encephalitis

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