Management of suspected viral encephalitis in children - Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines

R. Kneen, B. D. Michael, E. Menson, B. Mehta, A. Easton, C. Hemingway, P. E. Klapper, A. Vincent, M. Lim, E. Carrol, T. Solomon

    Research output: Contribution to journalArticlepeer-review

    Abstract

    In the 1980s the outcome of patients with herpes simplex encephalitis was shown to be dramatically improved with aciclovir treatment. Delays in starting treatment, particularly beyond 48 h after hospital admission, are associated with a worse prognosis. Several comprehensive reviews of the investigation and management of encephalitis have been published. However, their impact on day-to-day clinical practice appears to be limited. The emergency management of meningitis in children and adults was revolutionised by the introduction of a simple algorithm as part of management guidelines.In February 2008 a group of clinicians met in Liverpool to begin the development process for clinical care guidelines based around a similar simple algorithm, supported by an evidence base, whose implementation is hoped would improve the management of patients with suspected encephalitis. © 2012.
    Original languageEnglish
    Pages (from-to)449-477
    Number of pages28
    JournalJournal Of Infection
    Volume64
    Issue number5
    DOIs
    Publication statusPublished - May 2012

    Keywords

    • Antibody-associated encephalitis
    • Encephalitis
    • Enterovirus
    • Herpes simplex virus
    • Immunocompromised
    • Varicella zoster virus
    • Viral encephalitis

    Fingerprint

    Dive into the research topics of 'Management of suspected viral encephalitis in children - Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines'. Together they form a unique fingerprint.

    Cite this