Manipulation of the osteoblast response to a Ti-6Al-4V titanium alloy using a high power diode laser

L. Hao; J. Lawrence; L. Li

doi:10.1016/j.apsusc.2005.01.165

Manipulation of the osteoblast response to a Ti-6Al-4V titanium alloy using a high power diode laser

L. Hao, J. Lawrence, L. Li

Mechanical and Aerospace Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

To improve the bone integration of titanium-based implants a high power diode laser (HPDL) was used to modify the material for improved osteoblast cell response. The surface properties of un-treated and HPDL treated samples were characterized. Contact angles for the un-treated and the HPDL modified titanium alloy (Ti-6Al-4V) were determined with selected biological liquids by the sessile drop technique. The analysis revealed that the wettability of the Ti-6Al-4V improved after HPDL laser treatment, indicating that better interaction with the biological liquids occurred. Moreover, an in vitro human fetal osteoblast cells (hFOB 1.19) evaluation revealed a more favourable cell response on the HPDL laser treated Ti-6Al-4V alloy than on either un-treated sample or a mechanically roughened sample. It was consequently determined that the HPDL provides more a controllable and effective technique to improve the biocompatibility of bio-metals. © 2005 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	602-606
Number of pages	4
Journal	Applied Surface Science
Volume	247
Issue number	1-4
DOIs	https://doi.org/10.1016/j.apsusc.2005.01.165
Publication status	Published - 15 Jul 2005

Keywords

High power diode laser
Osteoblast cell
Titanium alloy
Wettability

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LPRC: Laser Processing Research Centre Impact
Allegre, O. (PI), Crosby, D. (PI), Domingos, M. (PI), Francis, J. (PI), Gillen, D. (PI), Guo, W. (PI), Li, L. (PI), Mativenga, P. (PI), Rogers, B. D. (PI), Whitehead, D. (PI), Wilson, D. (PI), Zhong, S. (PI), Mirhosseini, N. (Researcher), Ouyang, J. (Researcher), Huang, Y. (Researcher), Wei, C. (Researcher), Cheng, D. (PGR student), Suryo Pratomo, E. (PGR student), Zhang, Z. (PGR student), Li, Z. (PGR student), Mo, H. (PGR student), Zhu, M. (PGR student), Li, Q. (PGR student), Liu, W. (PGR student), Wang, L. (PGR student), Guo, H. (PGR student), Heinemann, R. (PI) & Liu, Z. (PI)
1/04/00 → …
Project: Research

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title = "Manipulation of the osteoblast response to a Ti-6Al-4V titanium alloy using a high power diode laser",

abstract = "To improve the bone integration of titanium-based implants a high power diode laser (HPDL) was used to modify the material for improved osteoblast cell response. The surface properties of un-treated and HPDL treated samples were characterized. Contact angles for the un-treated and the HPDL modified titanium alloy (Ti-6Al-4V) were determined with selected biological liquids by the sessile drop technique. The analysis revealed that the wettability of the Ti-6Al-4V improved after HPDL laser treatment, indicating that better interaction with the biological liquids occurred. Moreover, an in vitro human fetal osteoblast cells (hFOB 1.19) evaluation revealed a more favourable cell response on the HPDL laser treated Ti-6Al-4V alloy than on either un-treated sample or a mechanically roughened sample. It was consequently determined that the HPDL provides more a controllable and effective technique to improve the biocompatibility of bio-metals. {\textcopyright} 2005 Elsevier B.V. All rights reserved.",

keywords = "High power diode laser, Osteoblast cell, Titanium alloy, Wettability",

author = "L. Hao and J. Lawrence and L. Li",

year = "2005",

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doi = "10.1016/j.apsusc.2005.01.165",

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journal = "Applied Surface Science",

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TY - JOUR

T1 - Manipulation of the osteoblast response to a Ti-6Al-4V titanium alloy using a high power diode laser

AU - Hao, L.

AU - Lawrence, J.

AU - Li, L.

PY - 2005/7/15

Y1 - 2005/7/15

N2 - To improve the bone integration of titanium-based implants a high power diode laser (HPDL) was used to modify the material for improved osteoblast cell response. The surface properties of un-treated and HPDL treated samples were characterized. Contact angles for the un-treated and the HPDL modified titanium alloy (Ti-6Al-4V) were determined with selected biological liquids by the sessile drop technique. The analysis revealed that the wettability of the Ti-6Al-4V improved after HPDL laser treatment, indicating that better interaction with the biological liquids occurred. Moreover, an in vitro human fetal osteoblast cells (hFOB 1.19) evaluation revealed a more favourable cell response on the HPDL laser treated Ti-6Al-4V alloy than on either un-treated sample or a mechanically roughened sample. It was consequently determined that the HPDL provides more a controllable and effective technique to improve the biocompatibility of bio-metals. © 2005 Elsevier B.V. All rights reserved.

AB - To improve the bone integration of titanium-based implants a high power diode laser (HPDL) was used to modify the material for improved osteoblast cell response. The surface properties of un-treated and HPDL treated samples were characterized. Contact angles for the un-treated and the HPDL modified titanium alloy (Ti-6Al-4V) were determined with selected biological liquids by the sessile drop technique. The analysis revealed that the wettability of the Ti-6Al-4V improved after HPDL laser treatment, indicating that better interaction with the biological liquids occurred. Moreover, an in vitro human fetal osteoblast cells (hFOB 1.19) evaluation revealed a more favourable cell response on the HPDL laser treated Ti-6Al-4V alloy than on either un-treated sample or a mechanically roughened sample. It was consequently determined that the HPDL provides more a controllable and effective technique to improve the biocompatibility of bio-metals. © 2005 Elsevier B.V. All rights reserved.

KW - High power diode laser

KW - Osteoblast cell

KW - Titanium alloy

KW - Wettability

U2 - 10.1016/j.apsusc.2005.01.165

DO - 10.1016/j.apsusc.2005.01.165

M3 - Article

SN - 0169-4332

VL - 247

SP - 602

EP - 606

JO - Applied Surface Science

JF - Applied Surface Science

IS - 1-4

ER -

Manipulation of the osteoblast response to a Ti-6Al-4V titanium alloy using a high power diode laser

Abstract

Keywords

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LPRC: Laser Processing Research Centre Impact

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