Mapping of genes and transcribed sequences in a gene rich 400-kb region on human chromosome 11p15.1-->p14

G M Caldwell, R L Eddy, C D Day, L H Haley, P R Cooper, S S Sait, F Hejtmancik, R J Smith, C C Morton, M J Higgins, T B Shows

Research output: Contribution to journalArticlepeer-review

Abstract

We have identified a number of transcribed sequences within a 400-kb interval on chromosome 11p15.1--> p14. Six genes and 13 novel transcripts including ESTs, cDNAs and exons have been identified and assigned to this region. Comparison of mRNA sequence with genomic sequence has enabled us to determine the exon/intron structure of four of the genes (NUCB2, PIK3C2A, RPS13 and OR7E14P).

Original languageEnglish
Pages (from-to)103-7
Number of pages5
JournalCytogenetics and Cell Genetics
Volume92
Issue number1-2
DOIs
Publication statusPublished - 2001

Keywords

  • Base Sequence
  • Chromosomes, Human, Pair 11
  • Cloning, Molecular
  • DNA, Complementary
  • Exons
  • Expressed Sequence Tags
  • Gene Order
  • Genes
  • Humans
  • In Situ Hybridization, Fluorescence
  • Introns
  • Multigene Family
  • Physical Chromosome Mapping
  • Pseudogenes
  • RNA, Messenger
  • Transcription, Genetic
  • Journal Article
  • Research Support, U.S. Gov't, P.H.S.

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