Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1

C C Morton, R Taub, A Diamond, M A Lane, G M Cooper, P Leder

Research output: Contribution to journalArticlepeer-review

Abstract

Blym-1, a transforming gene detected by transfection of NIH 3T3 cells with DNA from Burkitt lymphomas, was mapped to the short arm of chromosome 1 (1p32) by chromosomal in situ hybridization. The Blym-1 gene was not physically linked to the cellular myc oncogene or to any of the immunoglobulin gene loci implicated in the characteristic chromosomal translocations in Burkitt lymphoma.

Original languageEnglish
Pages (from-to)173-5
Number of pages3
JournalScience
Volume223
Issue number4632
Publication statusPublished - 13 Jan 1984

Keywords

  • Base Sequence
  • Burkitt Lymphoma
  • Chromosome Aberrations
  • Chromosome Mapping
  • Chromosomes, Human, 1-3
  • Genetic Linkage
  • Humans
  • Immunoglobulins
  • Male
  • Nucleic Acid Hybridization
  • Oncogenes
  • Translocation, Genetic
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

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